Pneumonia in Bhutanese children: what we know, and what we need to know.

Sophie Jullien, Dinesh Pradhan, Quique Bassat
Author Information
  1. Sophie Jullien: 1ISGlobal, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
  2. Dinesh Pradhan: Khesar Gyalpo University of Medical Sciences of Bhutan (KGUMSB), Thimphu, Bhutan.
  3. Quique Bassat: 1ISGlobal, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.

Abstract

BACKGROUND: Pneumonia is the single largest cause of death in under-five children worldwide. We conducted a systematic review to identify the knowledge gaps around childhood pneumonia in Bhutan.
METHODS: We searched PubMed, ScienceDirect and Google scholar from conception to 3rd December 2018, World Health Organization, UNICEF, Bhutan's Ministry of Health and other local databases for relevant reports. We included any report describing pneumonia in Bhutanese children with regards to the burden of the disease, aetiology, related risk factors, clinical and prognostic characteristics, surveillance systems and national preventive strategies. Two review authors identified the records. We summarized the findings narratively.
RESULTS: We included 44 records. Although with notable decreasing trends, pneumonia is still accountable for a high burden and mortality rate in Bhutanese children. The national surveillance system focuses mainly on influenza identification but has recently introduced other viral aetiology to monitor. We found very scarce or no data with regard to the bacterial aetiology, related risk factors and clinico-radiological and prognostic characteristics.
CONCLUSION: There is a dearth of data regarding the epidemiological, microbiological, clinical and radiological characteristics of pneumonia in children in Bhutan, leading to challenges while implementing evidence-based management and effective national preventive strategies.

Keywords

References

  1. Vaccine. 2018 Mar 20;36(13):1757-1765 [PMID: 29478752]
  2. Influenza Other Respir Viruses. 2019 Jan;13(1):28-35 [PMID: 30137672]
  3. Pediatr Pulmonol. 2014 May;49(5):430-4 [PMID: 24610581]
  4. Acta Paediatr. 1995 Sep;84(9):1029-34 [PMID: 8652954]
  5. Lancet. 2017 Dec 17;388(10063):3027-3035 [PMID: 27839855]
  6. Lancet Infect Dis. 2017 Nov;17(11):1133-1161 [PMID: 28843578]
  7. Thorax. 2013 Nov;68(11):1052-6 [PMID: 23956020]
  8. Arch Dis Child. 2015 Feb;100 Suppl 1:S23-8 [PMID: 25613963]
  9. Arch Bronconeumol. 2015 Jan;51(1):5-9 [PMID: 24666712]
  10. Lancet. 2013 Apr 20;381(9875):1405-1416 [PMID: 23582727]
  11. Clin Infect Dis. 2012 Apr;54 Suppl 2:S109-16 [PMID: 22403224]
  12. Bull World Health Organ. 2019 Jun 01;97(6):386-393 [PMID: 31210676]
  13. Int J Microbiol. 2018 Oct 28;2018:8945142 [PMID: 30510579]
  14. Lancet Infect Dis. 2018 Nov;18(11):1191-1210 [PMID: 30243584]
  15. Influenza Other Respir Viruses. 2013 May;7(3):426-30 [PMID: 22813389]
  16. Pneumonia (Nathan). 2016 Aug 22;8:14 [PMID: 28702293]

Word Cloud

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