Computational Identification of Small Interfering RNA Targets in SARS-CoV-2. - National Genomics Data Center (CNCB-NGDC)

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Computational Identification of Small Interfering RNA Targets in SARS-CoV-2.

Wei Chen, Pengmian Feng, Kewei Liu, Meng Wu, Hao Lin

Author Information

Wei Chen: Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. greatchen@ncst.edu.cn. ORCID
Pengmian Feng: Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Kewei Liu: Center for Genomics and Computational Biology, School of Life Sciences, North China University of Science and Technology, Tangshan, 063210, China.
Meng Wu: Center for Genomics and Computational Biology, School of Life Sciences, North China University of Science and Technology, Tangshan, 063210, China.
Hao Lin: Key Laboratory for Neuro-Information of Ministry of Education, School of Life Science and Technology, Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, 610054, China. hlin@uestc.edu.cn. ORCID

PMID: 32297156 DOI: 10.1007/s12250-020-00221-6

No abstract text available.

J Med Virol. 2020 Apr;92(4):455-459 [PMID: 31994738]
Cell Res. 2005 Mar;15(3):193-200 [PMID: 15780182]
N Engl J Med. 2020 Feb 20;382(8):727-733 [PMID: 31978945]
Yi Chuan. 2020 Feb 20;42(2):212-221 [PMID: 32102777]
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2783-8 [PMID: 12594341]
Nature. 2001 May 24;411(6836):494-8 [PMID: 11373684]
Annu Rev Pharmacol Toxicol. 2016;56:103-22 [PMID: 26738473]
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2718-23 [PMID: 12594334]
Bioinformatics. 2002 Dec;18(12):1567-75 [PMID: 12490440]
Expert Opin Ther Targets. 2008 May;12(5):637-45 [PMID: 18410245]
Gene Ther. 2005 May;12(9):751-61 [PMID: 15772689]
Nucleic Acids Res. 2013 Jul;41(Web Server issue):W471-4 [PMID: 23620284]
Cell Res. 2020 Mar;30(3):189-190 [PMID: 32071427]
Infect Genet Evol. 2020 Apr;79:104211 [PMID: 32007627]

Betacoronavirus

COVID-19

Coronavirus Infections

Humans

Pandemics

Pneumonia, Viral

RNA, Small Interfering

Severe acute respiratory syndrome-related coronavirus

SARS-CoV-2

RNA, Small Interfering

Letter Comment

A small interfering RNA (siRNA) database for SARS-CoV-2.A Computational Approach for Designing and Validating Small Interfering RNA against SARS-CoV-2 Variants.SARS-CoV-2 targets ribosomal RNA biogenesis.Inhibition of SARS-CoV-2 Replication by a Small Interfering RNA Targeting the Leader Sequence.Identification and computational analysis of mutations in SARS-CoV-2.Computational Identification of SARS-CoV-2 Inhibitor in , .A synthetic defective interfering SARS-CoV-2.Silencing of SARS-CoV spike gene by small interfering RNA in HEK 293T cells.Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data.Small interfering RNA inhibits SARS-CoV nucleocapsid gene expression in cultured cells and mouse muscles.

An in silico analysis of effective siRNAs against COVID-19 by targeting the leader sequence of SARS-CoV-2.Prediction of potential small interfering RNA molecules for silencing of the spike gene of SARS-CoV-2.Design of siRNAs Targeting Existing and Future Respiratory Viruses with VirusSi.Identification of Causal Genes of COVID-19 Using the SMR Method.In silico prediction and experimental evaluation of potential siRNAs against SARS-CoV-2 inhibition in Vero E6 cells.Are Viral Vectors Any Good for RNAi Antiviral Therapy?Effect of insilico predicted and designed potential siRNAs on inhibition of SARS-CoV-2 in HEK-293 cells.Can CRISPR/Cas Technology Be a Felicitous Stratagem Against the COVID-19 Fiasco? Prospects and Hitches.Potential Achilles heels of SARS-CoV-2 are best displayed by the base order-dependent component of RNA folding energy.Conserved MicroRNAs in Human Nasopharynx Tissue Samples from Swabs Are Differentially Expressed in Response to SARS-CoV-2.

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