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Molecules (Basel, Switzerland)
Apr 16, 2020;25 (8):

and : From Ethnobotanical Surveys to Phytochemical Characterization and Bioactivities Evaluation.

Eugénia Solange Santos, Ângelo Luís, Joana Gonçalves, Tiago Rosado, Luísa Pereira, Eugenia Gallardo, Ana Paula Duarte
Author Information
  1. Eugénia Solange Santos: Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.
  2. Ângelo Luís: Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal. ORCID
  3. Joana Gonçalves: Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.
  4. Tiago Rosado: Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal. ORCID
  5. Luísa Pereira: Centro de Matemática e Aplicações (CMA-UBI), Universidade da Beira Interior, Rua Marquês d'Ávila e Bolama, 6201-001 Covilhã, Portugal.
  6. Eugenia Gallardo: Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal. ORCID
  7. Ana Paula Duarte: Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.
PMID: 32316213 DOI: 10.3390/molecules25081828

Abstract

and are two plant species with important application in African traditional medicine, particularly in Angola, in the treatment of several diseases. However, scientific studies concerning these species are scarce. The goal of this work was to know better which medicinal approaches are used by the Huíla population in Angola by means of ethnobotanical surveys. Furthermore, extracts of both plants were phytochemically characterized. Antioxidant, anti-inflammatory, wound-healing activities, and potential cytotoxicity were also studied. With this study it was possible to verify that 67% of the individuals that use medicinal plants are women, and their main therapeutic uses are the treatment of problems of the digestive system and skin disorders. Barks of and leaves of are the most often used plant parts. Through high-performance liquid chromatography coupled to diode-array detector (HPLC-DAD) and GC-MS it was possible to characterize the chemical composition of the two species, which are rich in phenolic compounds, terpenes, terpenoids, sesquiterpenoids and fatty acids. Both plants showed to possess antioxidant, anti-inflammatory proprieties, and wound-healing activity. To the best of our knowledge, this is the most comprehensive study of these two species and the first ethnobotanical and ethnopharmacological study of medicinal plants from this region of Angola.

Keywords

GC-MS HPLC-DAD Julbernardia paniculata Pterocarpus angolensis ethnobotanical surveys phytochemicals wound-healing activity

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Grants

  1. UIDB/00709/2020/Fundação para a Ciência e a Tecnologia
  2. Presentation Guide Number: 459/2016/Instituto Nacional de Gestão de Bolsas de Estudo
  3. Reference: SFRH/BD/149360/2019/Fundação para a Ciência e a Tecnologia
  4. CENTRO-01-0145-FEDER-000019-C4/Horizon 2020

MeSH Term

Adult
Angola
Anti-Inflammatory Agents
Antioxidants
Cell Line
Chromatography, High Pressure Liquid
Ethnopharmacology
Fabaceae
Female
Gas Chromatography-Mass Spectrometry
Humans
Male
Models, Biological
Phytochemicals
Pterocarpus
Wound Healing

Chemicals

Anti-Inflammatory Agents
Antioxidants
Phytochemicals
Journal Article
Article has an altmetric score of 1

Word Cloud

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