The Israeli Phage Bank (IPB).

Ortal Yerushalmy, Leron Khalifa, Naama Gold, Chani Rakov, Sivan Alkalay-Oren, Karen Adler, Shira Ben-Porat, Reut Kraitman, Niv Gronovich, Kerem Shulamit Ginat, Mohanad Abdalrhman, Shunit Coppenhagen-Glazer, Ran Nir-Paz, Ronen Hazan
Author Information
  1. Ortal Yerushalmy: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  2. Leron Khalifa: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  3. Naama Gold: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  4. Chani Rakov: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  5. Sivan Alkalay-Oren: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  6. Karen Adler: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  7. Shira Ben-Porat: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  8. Reut Kraitman: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  9. Niv Gronovich: Alpha Program, Future Scientists Center for the Advancement of the Gifted and Talented, Jerusalem 9190401, Israel.
  10. Kerem Shulamit Ginat: Alpha Program, Future Scientists Center for the Advancement of the Gifted and Talented, Jerusalem 9190401, Israel.
  11. Mohanad Abdalrhman: Hadassah Medical Center, Department of Infectious Diseases, Jerusalem 91120, Israel.
  12. Shunit Coppenhagen-Glazer: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
  13. Ran Nir-Paz: Hadassah Medical Center, Department of Infectious Diseases, Jerusalem 91120, Israel.
  14. Ronen Hazan: Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel. ORCID

Abstract

A key element in phage therapy is the establishment of large phage collections, termed herein "banks", where many well-characterized phages, ready to be used in the clinic, are stored. These phage banks serve for both research and clinical purposes. Phage banks are also a key element in clinical phage microbiology, the prior treatment matching of phages and antibiotics to specific bacterial targets. A worldwide network of phage banks can promote a phage-based solution for any isolated bacteria. Herein, we describe the Israeli Phage Bank (IPB) established in the Hebrew University, Jerusalem, which currently has over 300 phages matching 16 bacteria, mainly pathogens. The phage bank is constantly isolating new phages and developing methods for phage isolation and characterization. The information on the phages and bacteria stored in the bank is available online.

Keywords

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Grants

  1. 2017123/United States - Israel Binational Science Foundation
  2. ISF_540_2017/Israel Science Foundation
  3. A2232/Rosetrees Trust

Word Cloud

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