Tenosynovial Giant Cell Tumor in an Infant.

Shawhin Shahriari, Ashley Ederle, James Botros, Hillary Elwood, Anil Shetty
Author Information
  1. Shawhin Shahriari: Department of Surgery, Division of Plastic, Reconstructive, Hand, and Burn Surgery.
  2. Ashley Ederle: Department of Internal Medicine.
  3. James Botros: Department of Neurosurgery.
  4. Hillary Elwood: Department of Pathology, University of New Mexico, Albuquerque, NM.
  5. Anil Shetty: Department of Surgery, Division of Plastic, Reconstructive, Hand, and Burn Surgery.

Abstract

In this report, the authors describe a child presenting at 6 months old with a rapidly expanding extracranial left temporal mass concerning for malignancy. The mass was successfully treated at 16 months with radical surgical excision. The patient was found to have a tenosynovial giant cell tumor, diffuse type, completely encased by the temporalis muscle. To our knowledge, this is the first report of a case of diffuse type tenosynovial giant cell tumor in the temporalis muscle, without articular involvement, presenting in an infant.

References

  1. Hu Y, Kuang B, Chen Y, et al. Imaging features for diffuse-type tenosynovial giant cell tumor of the temporomandibular joint: a case report. Medicine (Baltimore) 2017; 96:e7383.
  2. Rateb K, Hassen BG, Leila A, et al. Giant cell tumor of soft tissues: a case report of extra-articular diffuse-type giant cell tumor of the quadriceps. Int J Surg Case Rep 2017; 31:245249.
  3. Son SM, Park YS, Choi CH, et al. Extra-articular tenosynovial giant cell tumor of diffuse type in the temporal area with brain parenchymal invasion: a case report. Br J Neurosurg 2018; 32:688690.
  4. Yan H, Wang F, Xiang L, et al. Diffuse giant cell tumors of the tendon sheath in temporomandibular joint: two case reports and review of the literature. Medicine (Baltimore) 2018; 97:e11101.
  5. Herman CR, Swift JQ, Schiffman EL. Pigmented villonodular synovitis of the temporomandibular joint with intracranial extension: a case and literature review. Int J Oral Maxillofac Surg 2009; 38:795801.
  6. Takeuchi A, Yamamoto N, Hayashi K, et al. Tenosynovial giant cell tumors in unusual locations detected by positron emission tomography imaging confused with malignant tumors: report of two cases. BMC Musculoskelet Disord 2016; 17:180.
  7. Somerhausen NSA, Fletcher CD. Diffuse-type giant cell tumor: clinicopathologic and immunohistochemical analysis of 50 cases with extraarticular disease. Am J Surg Pathol 2000; 24:479492.
  8. Yun SJ, Hwang SY, Jin W, et al. Intramuscular diffuse-type tenosynovial giant cell tumor of the deltoid muscle in a child. Skeletal Radiol 2014; 43:11791183.
  9. Cassier PA, Italiano A, Gomez-Roca CA, et al. CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study. Lancet Oncol 2015; 16:949956.
  10. van der Heijden L, Gibbons CL, Dijkstra PD, et al. The management of diffuse-type giant cell tumour (pigmented villonodular synovitis) and giant cell tumour of tendon sheath (nodular tenosynovitis). J Bone Joint Surg Br 2012; 94:882888.

MeSH Term

Female
Giant Cell Tumor of Tendon Sheath
Humans
Infant
Synovitis, Pigmented Villonodular

Word Cloud

Created with Highcharts 10.0.0reportpresentingmonthsmasstenosynovialgiantcelltumordiffusetypetemporalismuscleauthorsdescribechild6oldrapidlyexpandingextracraniallefttemporalconcerningmalignancysuccessfullytreated16radicalsurgicalexcisionpatientfoundcompletelyencasedknowledgefirstcasewithoutarticularinvolvementinfantTenosynovialGiantCellTumorInfant

Similar Articles

Cited By