Recent years have seen an increasing interest in quantum chaos and related aspects of spatially extended systems, such as spin chains. However, the results are strongly system dependent: generic approaches suggest the presence of many-body localization, while analytical calculations for certain system classes, here referred to as the "self-dual case," prove adherence to universal (chaotic) spectral behavior. We address these issues studying the level statistics in the vicinity of the latter case, thereby revealing transitions to many-body localization as well as the appearance of several nonstandard random-matrix universality classes.