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Microbial genomics
09, 2020;6 (9):

Comparative genomic insights into - a commonly misidentified -like organism.

Scott Van Nguyen, Dechamma Mundanda Muthappa, Athmanya K Eshwar, James F Buckley, Brenda P Murphy, Roger Stephan, Angelika Lehner, Séamus Fanning
Author Information
  1. Scott Van Nguyen: UCD-Centre for Food Safety, School of Public Health, Physiotherapy & Sports Science, University College Dublin, Belfield, Dublin D04 N2E5, Ireland.
  2. Dechamma Mundanda Muthappa: UCD-Centre for Food Safety, School of Public Health, Physiotherapy & Sports Science, University College Dublin, Belfield, Dublin D04 N2E5, Ireland.
  3. Athmanya K Eshwar: Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
  4. James F Buckley: Veterinary Food Safety Laboratory, Cork County Council, Inniscarra, Co. Cork and Department of Microbiology, National University of Ireland, Cork, College Road, Cork, Ireland.
  5. Brenda P Murphy: Veterinary Food Safety Laboratory, Cork County Council, Inniscarra, Co. Cork and Department of Microbiology, National University of Ireland, Cork, College Road, Cork, Ireland.
  6. Roger Stephan: Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
  7. Angelika Lehner: Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
  8. Séamus Fanning: UCD-Centre for Food Safety, School of Public Health, Physiotherapy & Sports Science, University College Dublin, Belfield, Dublin D04 N2E5, Ireland.
PMID: 32701425 DOI: 10.1099/mgen.0.000411

Abstract

Food-associated outbreaks linked to enteropathogenic are of concern to public health. Pigs and their meat are recognized risk factors for transmission of . This study aimed to describe the comparative genomics of along with a number of misclassified isolates, now constituting the recently described . The latter was originally cultured from an environmental sample taken at a pig slaughterhouse. Unique features were identified in the genome of including a novel integrative conjugative element (ICE), denoted as ICE contained within a 255 kbp region of plasticity. In addition, a zebrafish embryo infection model was adapted and applied to assess the virulence potential among isolates including .

Keywords

Yersinia enterocolitica Yersinia hibernica comparative genomics zebrafish embryo

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MeSH Term

Animals
Conjugation, Genetic
Diagnosis, Differential
Disease Models, Animal
Embryo, Nonmammalian
Food Microbiology
Genomics
Phylogeny
Swine
Virulence Factors
Yersinia
Yersinia Infections
Yersinia enterocolitica
Zebrafish

Chemicals

Virulence Factors
Journal Article

Word Cloud

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