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Journal of neurology
Jan, 2021;268 (1): 377-385.

Diagnosing vestibular hypofunction: an update.

Dmitrii Starkov, Michael Strupp, Maksim Pleshkov, Herman Kingma, Raymond van de Berg
Author Information
  1. Dmitrii Starkov: Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands. dmitrii.n.starkov@gmail.com. ORCID
  2. Michael Strupp: German Center for Vertigo and Balance Disorders, Ludwig Maximilians University, Munich, Germany.
  3. Maksim Pleshkov: Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.
  4. Herman Kingma: Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.
  5. Raymond van de Berg: Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.
PMID: 32767115 DOI: 10.1007/s00415-020-10139-4

Abstract

Unilateral or bilateral vestibular hypofunction presents most commonly with symptoms of dizziness or postural imbalance and affects a large population. However, it is often missed because no quantitative testing of vestibular function is performed, or misdiagnosed due to a lack of standardization of vestibular testing. Therefore, this article reviews the current status of the most frequently used vestibular tests for canal and otolith function. This information can also be used to reach a consensus about the systematic diagnosis of vestibular hypofunction.

Keywords

Bilateral vestibulopathy Caloric testing Dynamic visual acuity Perceptual threshold Unilateral vestibulopathy Vestibular evoked myogenic potentials Video-head impulse test Video-oculography

References

  1. Acta Otolaryngol Suppl. 1995;520 Pt 2:343-6 [PMID: 8749157]
  2. Otolaryngology. 1978 Jan-Feb;86(1):ORL-130-42 [PMID: 114912]
  3. Front Neurol. 2016 Apr 20;7:58 [PMID: 27148159]
  4. Am J Otolaryngol. 1982 May-Jun;3(3):182-8 [PMID: 7102956]
  5. Laryngoscope. 2018 Oct;128(10):2383-2389 [PMID: 29447427]
  6. Audiol Neurootol. 2017;22(4-5):282-291 [PMID: 29324449]
  7. Semin Neurol. 2020 Feb;40(1):18-32 [PMID: 31935772]
  8. Eur Arch Otorhinolaryngol. 2020 Mar;277(3):679-686 [PMID: 31749057]
  9. Front Neurol. 2017 Aug 18;8:419 [PMID: 28868046]
  10. J Neurol Neurosurg Psychiatry. 1994 Feb;57(2):190-7 [PMID: 8126503]
  11. Clin Otolaryngol Allied Sci. 1986 Jun;11(3):161-9 [PMID: 3488145]
  12. Acta Otolaryngol. 2020 Sep;140(9):728-735 [PMID: 32437211]
  13. Otol Neurotol. 2002 May;23(3):372-7 [PMID: 11981398]
  14. PLoS One. 2020 Jan 15;15(1):e0227406 [PMID: 31940394]
  15. Brain Res Bull. 1996;40(5-6):443-7; discussion 448-9 [PMID: 8886372]
  16. J Vestib Res. 2019;29(4):161-170 [PMID: 31306146]
  17. J Neurol Sci. 1995 Sep;132(1):35-43 [PMID: 8523028]
  18. J Aud Res. 1979 Apr;19(2):127-35 [PMID: 549907]
  19. Otol Neurotol. 2016 Oct;37(9):1399-405 [PMID: 27556420]
  20. J Neurol. 2022 Oct;269(10):5216-5228 [PMID: 34263351]
  21. Exp Brain Res. 2008 Apr;186(4):677-81 [PMID: 18350283]
  22. Ear Hear. 2020 Mar/Apr;41(2):323-329 [PMID: 31517671]
  23. Front Neurol. 2017 Jan 25;8:15 [PMID: 28179894]
  24. Exp Brain Res. 2013 Apr;226(2):231-40 [PMID: 23392475]
  25. Front Neurol. 2018 Aug 17;9:659 [PMID: 30174641]
  26. Front Neurol. 2019 Apr 16;10:365 [PMID: 31105632]
  27. J Vestib Res. 2014;24(5-6):459-64 [PMID: 25564089]
  28. Neurol Clin Pract. 2018 Apr;8(2):129-134 [PMID: 29708189]
  29. Am J Audiol. 2018 Mar 08;27(1):104-109 [PMID: 29383375]
  30. Int J Audiol. 2020 May;59(5):333-340 [PMID: 31855087]
  31. Semin Neurol. 2020 Feb;40(1):5-17 [PMID: 31935767]
  32. J Am Acad Audiol. 2017 Oct;28(9):778-785 [PMID: 28972467]
  33. J Assoc Res Otolaryngol. 2013 Dec;14(6):905-15 [PMID: 24077672]
  34. Front Neurol. 2020 Apr 21;11:289 [PMID: 32390929]
  35. Front Neurol. 2019 Jan 04;9:1138 [PMID: 30662427]
  36. Int J Pediatr Otorhinolaryngol. 2019 Oct;125:206-211 [PMID: 31415955]
  37. Laryngoscope. 2020 Dec;130(12):E918-E925 [PMID: 32031698]
  38. Acta Otolaryngol. 2015 Sep;135(9):886-94 [PMID: 25857220]
  39. Front Neurol. 2016 Mar 04;7:26 [PMID: 26973594]
  40. Otol Neurotol. 2011 Jul;32(5):812-7 [PMID: 21512425]
  41. Laryngoscope. 2019 Jul;129(7):1660-1666 [PMID: 30515842]
  42. Audiol Neurootol. 2018;23(6):335-344 [PMID: 30677753]
  43. Exp Brain Res. 2020 May;238(5):1237-1248 [PMID: 32279086]
  44. Acta Otorhinolaryngol Belg. 1998;52(3):207-14 [PMID: 9810455]
  45. Otol Neurotol. 2016 Aug;37(7):933-6 [PMID: 27295442]
  46. Acta Otolaryngol. 2018 Sep;138(9):785-789 [PMID: 30016899]
  47. Ear Hear. 2019 Jul/Aug;40(4):878-886 [PMID: 30431457]
  48. Arch Neurol. 1988 Jul;45(7):737-9 [PMID: 3390028]
  49. Clin Neurophysiol. 2014 Apr;125(4):658-666 [PMID: 24513390]
  50. J Neurol. 2020 Dec;267(Suppl 1):256-264 [PMID: 32719974]
  51. Clin Neurophysiol. 2020 Jul;131(7):1664-1671 [PMID: 32089450]
  52. Front Neurol. 2019 Apr 16;10:328 [PMID: 31040813]
  53. Otolaryngol Head Neck Surg. 2018 Oct;159(4):739-742 [PMID: 29865935]
  54. Front Neurol. 2018 Jun 04;9:352 [PMID: 29915554]
  55. J Neurol. 2018 Oct;265(Suppl 1):35-39 [PMID: 29868981]
  56. Acta Otolaryngol Suppl. 1989;468:323-7 [PMID: 2635526]
  57. Ear Hear. 2020 Sep/Oct;41(5):1111-1124 [PMID: 32032225]
  58. J Vestib Res. 2017;27(4):177-189 [PMID: 29081426]
  59. Front Neurol. 2013 Oct 25;4:165 [PMID: 24298265]
  60. Handb Clin Neurol. 2016;137:177-86 [PMID: 27638070]
  61. Clinics (Sao Paulo). 2017 Aug;72(8):469-473 [PMID: 28954005]
  62. Front Neurol. 2018 Jun 11;9:396 [PMID: 29942279]
  63. Otol Neurotol. 2020 Jan;41(1):e76-e82 [PMID: 31789804]
  64. J Vestib Res. 2011;21(6):323-30 [PMID: 22348937]
  65. Adv Otorhinolaryngol. 1988;41:190-5 [PMID: 3213699]
  66. J Vestib Res. 2010;20(1):71-7 [PMID: 20555169]
  67. Int Tinnitus J. 2019 Sep 04;23(2):69-73 [PMID: 32009337]
  68. Gait Posture. 2018 Sep;65:137-142 [PMID: 30558920]
  69. Ear Hear. 2020 Sep/Oct;41(5):1397-1406 [PMID: 32058350]
  70. Am J Audiol. 2019 Aug 28;28(2S):414-421 [PMID: 31461337]
  71. Semin Neurol. 2013 Jul;33(3):195-203 [PMID: 24057822]
  72. Front Neurol. 2012 Mar 23;3:39 [PMID: 22470364]
  73. Front Neurol. 2016 Sep 23;7:160 [PMID: 27721805]
  74. Braz J Otorhinolaryngol. 2010 May-Jun;76(3):399-403 [PMID: 20658023]
  75. Otol Neurotol. 2016 Dec;37(10):1614-1619 [PMID: 27668791]
  76. Otol Neurotol. 2020 Jul;41(6):828-835 [PMID: 32271263]
  77. Percept Psychophys. 2001 Nov;63(8):1421-55 [PMID: 11800466]
  78. ORL J Otorhinolaryngol Relat Spec. 2019;81(4):193-201 [PMID: 31390639]
  79. Curr Opin Neurol. 2018 Feb;31(1):111-116 [PMID: 29189298]
  80. Front Neurol. 2014 Oct 30;5:223 [PMID: 25400618]
  81. J Vestib Res. 2008;18(4):197-208 [PMID: 19208964]
  82. Acta Otolaryngol. 1989 Nov-Dec;108(5-6):345-54 [PMID: 2589064]
  83. Contemp Neurol Ser. 1979;18:1-21 [PMID: 378525]
  84. Laryngoscope. 2014 Jun;124(6):1431-5 [PMID: 24114593]
  85. Prog Neurobiol. 1993 Oct;41(4):435-72 [PMID: 8210413]
  86. Am J Otol. 1994 May;15(3):340-7 [PMID: 8579138]
  87. Front Neurol. 2017 Jun 09;8:258 [PMID: 28649224]
  88. J Vestib Res. 2016 Nov 3;26(4):395-402 [PMID: 27814315]
  89. Acta Otolaryngol. 2019 Jun;139(6):500-504 [PMID: 30957614]
  90. Int J Audiol. 2004 May;43(5):276-82 [PMID: 15357411]
  91. Percept Psychophys. 2001 Nov;63(8):1279-92 [PMID: 11800457]
  92. Exp Brain Res. 2002 Feb;142(4):486-95 [PMID: 11845244]
  93. J Vestib Res. 2011;21(3):117-25 [PMID: 21558637]
  94. J Vestib Res. 2017;27(2-3):163-172 [PMID: 29064828]
  95. Clin Neurophysiol. 2019 Sep;130(9):1539-1556 [PMID: 31299589]
  96. J Neurol. 2018 Oct;265(Suppl 1):40-43 [PMID: 30083955]
  97. ORL J Otorhinolaryngol Relat Spec. 2015 Sep 15;77(4):197-218 [PMID: 26366566]
  98. J Neurophysiol. 1981 Oct;46(4):878-99 [PMID: 7288469]
  99. Curr Opin Neurol. 2020 Feb;33(1):126-135 [PMID: 31789675]
  100. Neurology. 2009 Oct 6;73(14):1134-41 [PMID: 19805730]
  101. Laryngoscope. 1991 Feb;101(2):192-6 [PMID: 1992272]
  102. Front Neurol. 2020 May 12;11:362 [PMID: 32528397]
  103. Arch Otolaryngol Head Neck Surg. 2010 Jul;136(7):686-91 [PMID: 20644064]
  104. Acta Otolaryngol Suppl. 1995;520 Pt 1:194-8 [PMID: 8749117]
  105. Acta Otolaryngol. 1990 Jan-Feb;109(1-2):15-24 [PMID: 2309554]
  106. J Neurol. 2019 Sep;266(Suppl 1):101-107 [PMID: 31073715]
  107. J Assoc Res Otolaryngol. 2005 Sep;6(3):191-206 [PMID: 16088383]
  108. Front Neurol. 2016 Oct 03;7:162 [PMID: 27752252]
  109. Neurology. 2016 Jul 26;87(4):410-8 [PMID: 27251884]
  110. Audiol Neurootol. 2020;25(1-2):91-95 [PMID: 31661687]
  111. Ear Hear. 2013 Nov-Dec;34(6):e65-73 [PMID: 23673615]
  112. Am J Otol. 1998 Nov;19(6):790-6 [PMID: 9831156]
  113. J Vestib Res. 2004;14(6):461-6 [PMID: 15735328]
  114. Clin Neurophysiol. 2010 Feb;121(2):132-44 [PMID: 19897412]
  115. Acta Otolaryngol. 1972 Apr;73(4):341-3 [PMID: 5045874]
  116. Front Neurol. 2019 Jul 02;10:707 [PMID: 31312176]
  117. Gait Posture. 2011 Apr;33(4):656-60 [PMID: 21435878]
  118. Neurology. 2017 Nov 28;89(22):2288-2296 [PMID: 29093067]
  119. Eur Arch Otorhinolaryngol. 2016 Oct;273(10):2931-9 [PMID: 26728484]
  120. Clin Neurophysiol Pract. 2019 Feb 26;4:37-38 [PMID: 30906907]
  121. BMC Ear Nose Throat Disord. 2005 Jun 22;5(1):5 [PMID: 15972096]
  122. Acta Otolaryngol. 2000 Sep;120(6):724-30 [PMID: 11099148]
  123. Laryngoscope. 2020 Dec;130(12):E911-E917 [PMID: 32031691]
  124. J Neurol. 2020 Dec;267(Suppl 1):265-272 [PMID: 33113022]
  125. Ear Hear. 2018 Nov/Dec;39(6):1199-1206 [PMID: 29624541]
  126. Eur Arch Otorhinolaryngol. 2019 Dec;276(12):3257-3265 [PMID: 31605189]
  127. Ear Hear. 2019 Mar/Apr;40(2):287-294 [PMID: 29889159]
  128. Lancet. 1999 Aug 28;354(9180):746 [PMID: 10475195]
  129. J Neurol. 2021 Feb;268(2):431-439 [PMID: 31222419]
  130. Eur Arch Otorhinolaryngol. 2016 Nov;273(11):3733-3739 [PMID: 27113255]
  131. Front Neurol. 2018 Dec 07;9:1076 [PMID: 30581415]
  132. Audiol Neurootol. 2015;20(1):39-50 [PMID: 25501133]
  133. Acta Otolaryngol. 2020 Feb;140(2):140-143 [PMID: 31859539]
  134. Arch Otolaryngol Head Neck Surg. 2012 Mar;138(3):301-6 [PMID: 22431876]
  135. Neurol Clin Pract. 2020 Oct;10(5):379-387 [PMID: 33299665]
  136. Clin Neurophysiol Pract. 2019 Feb 26;4:47-68 [PMID: 30949613]

MeSH Term

Dizziness
Head Impulse Test
Humans
Otolithic Membrane
Vertigo
Vestibule, Labyrinth
Journal Article Review
Article has an altmetric score of 10

Word Cloud

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