- Letizia Angiolella: Department of Public Health and Infectious Diseases "Sapienza", University of Rome, Piazzale Aldo Moro, Rome, Italy. ORCID
The antifungal activity of essential oil (PCEO) and essential oil (CMEO) against were evaluated. The main components of essential oils were β-cytronellol 58.81% and geraniol 83.94% in PCEO and CMEO, respectively. PCEO was more activity than CMEO for all strains tested with values MIC or MIC of 780 µg/ml. PCEO used in combination with fluconazole or CMEO shows synergistic effect with FICI values ≤ 0.5. Moreover both essential oils are able to inhibit the major virulence factor of as the germ tube formation at sub-inhibitory concentration of 195 µg/ml. In conclusion, it is possible to hypothesize that PCEO can be used in combination with fluconazole or CMEO. Further studies are in due course to confirm these results.