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Emerging infectious diseases
10, 2020;26 (10): 2511-2513.

Macrolide-Resistant Bordetella pertussis, Vietnam, 2016-2017.

Kazunari Kamachi, Hong T Duong, Anh D Dang, T Hai, Do Do, Kentaro Koide, Nao Otsuka, Keigo Shibayama, Ha Thi Thu Hoang
Author Information
PMID: 32946738 DOI: 10.3201/eid2610.201035

Abstract

Macrolide-resistant Bordetella pertussis emerged in Vietnam during 2016-2017. Direct analyses of swab samples from 10 patients with pertussis revealed a macrolide-resistant mutation, A2047G, in the 23S rRNA. We identified the MT104 genotype of macrolide-resistant B. pertussis (which is prevalent in mainland China) and its variants in these patients.

Keywords

23S rRNA A2047G mutation Bordetella pertussis Vietnam antimicrobial resistance bacteria genotyping macrolide resistance respiratory infections

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MeSH Term

Anti-Bacterial Agents
Bordetella pertussis
China
Drug Resistance, Bacterial
Erythromycin
Humans
Macrolides
RNA, Ribosomal, 23S
Vietnam

Chemicals

Anti-Bacterial Agents
Macrolides
RNA, Ribosomal, 23S
Erythromycin
Journal Article Research Support, Non-U.S. Gov't
Article has an altmetric score of 99

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