Antioxidant and α-glucosidase inhibitory capacity of nonextractable polyphenols in Mopan persimmon.

Chang Zhou, Kemin Mao, Jiao Li, Jie Gao, Xiaoyu Liu, Yaxin Sang
Author Information
  1. Chang Zhou: College of Food Science and Technology Hebei Agricultural University Baoding China.
  2. Kemin Mao: College of Food Science and Technology Hebei Agricultural University Baoding China.
  3. Jiao Li: College of Food Science and Technology Hebei Agricultural University Baoding China.
  4. Jie Gao: College of Food Science and Technology Hebei Agricultural University Baoding China.
  5. Xiaoyu Liu: College of Food Science and Technology Hebei Agricultural University Baoding China.
  6. Yaxin Sang: College of Food Science and Technology Hebei Agricultural University Baoding China. ORCID

Abstract

This study was to evaluate and compare the polyphenols contents, antioxidant capacities, and α-glucosidase inhibitory abilities of extractable and nonextractable polyphenols (EP and NEP) in Mopan persimmon. The results showed that total phenols content of NEP was 5 times higher than that of EP, and the hydrolyzed NEP compounds displayed higher antioxidant capacity than EP in vitro by DPPH, ORAC assays. Meanwhile, NEP also exhibited inhibition capacity of α-glucosidase and were higher than that of acarbose. In addition, an in vitro model of gastrointestinal digestion was used for the release of NEP, the polyphenols content and ORAC values were obviously increased in gastric digestion stage. The result indicated that NEP in Mopan persimmon, which has often been overlooked and discarded in the past, possessed higher polyphenols content and antioxidant capacity than EP.

Keywords

References

  1. Food Sci Biotechnol. 2017 May 29;26(3):563-571 [PMID: 30263580]
  2. J Food Sci. 2011 Sep;76(7):T163-72 [PMID: 22417564]
  3. Anal Bioanal Chem. 2017 May;409(14):3645-3655 [PMID: 28331956]
  4. Oxid Med Cell Longev. 2009 Nov-Dec;2(5):270-8 [PMID: 20716914]
  5. Food Funct. 2016 Jul 13;7(7):3252-62 [PMID: 27364042]
  6. Int J Food Sci Nutr. 2012 Dec;63(8):936-9 [PMID: 22524561]
  7. Food Sci Nutr. 2019 Apr 12;7(5):1584-1594 [PMID: 31139371]
  8. Mol Nutr Food Res. 2010 Nov;54(11):1646-58 [PMID: 20540148]
  9. Food Chem. 2018 Jul 30;255:23-30 [PMID: 29571471]
  10. J Ethnopharmacol. 2015 Apr 2;163:229-40 [PMID: 25637828]
  11. J Agric Food Chem. 2005 Apr 6;53(7):2760-6 [PMID: 15796622]
  12. J Chromatogr A. 2017 Sep 8;1514:1-15 [PMID: 28778531]
  13. J Natl Cancer Inst. 2000 Jan 5;92(1):61-8 [PMID: 10620635]
  14. Food Sci Nutr. 2019 Apr 02;7(5):1555-1563 [PMID: 31139368]
  15. J Environ Radioact. 2016 Oct;162-163:182-188 [PMID: 27267156]
  16. J Food Drug Anal. 2016 Jul;24(3):627-634 [PMID: 28911570]
  17. Food Sci Nutr. 2018 Oct 20;6(8):1991-1998 [PMID: 30510699]
  18. Biomed Res Int. 2016;2016:4287461 [PMID: 27648444]
  19. J Enzyme Inhib Med Chem. 2016;31(sup4):200-210 [PMID: 27595863]
  20. Food Funct. 2017 May 24;8(5):1942-1954 [PMID: 28470323]
  21. Food Chem. 2011 Sep 1;128(1):14-21 [PMID: 25214323]
  22. Food Sci Nutr. 2018 Oct 26;6(8):2473-2490 [PMID: 30510749]
  23. J Alzheimers Dis. 2017;59(2):481-501 [PMID: 28582855]
  24. Int J Epidemiol. 2017 Jun 1;46(3):1029-1056 [PMID: 28338764]
  25. J Agric Food Chem. 2009 Aug 26;57(16):7298-303 [PMID: 19637929]
  26. Food Chem. 2016 Jul 1;202:99-103 [PMID: 26920271]
  27. J Nutr Metab. 2013;2013:708381 [PMID: 23936637]
  28. J Agric Food Chem. 2005 Apr 6;53(7):2433-40 [PMID: 15796575]
  29. J Food Sci. 2008 Jan;73(1):C24-8 [PMID: 18211345]
  30. J Agric Food Chem. 2012 Nov 14;60(45):11195-200 [PMID: 23095074]
  31. Biol Pharm Bull. 2014;37(7):1119-23 [PMID: 24805207]
  32. Food Chem. 2008 May 15;108(2):519-32 [PMID: 26059130]
  33. Mini Rev Med Chem. 2010 Apr;10(4):315-31 [PMID: 20470247]
  34. Int J Cancer. 2012 Aug 15;131(4):E544-54 [PMID: 22072493]
  35. Food Sci Nutr. 2020 Sep 12;8(10):5729-5737 [PMID: 33133574]
  36. J Sep Sci. 2008 Oct;31(20):3519-26 [PMID: 18830958]

Word Cloud

Created with Highcharts 10.0.0NEPpolyphenolscapacityEPhigherantioxidantα-glucosidaseMopanpersimmoncontentvitrodigestioninhibitorynonextractableORACAntioxidantstudyevaluatecomparecontentscapacitiesabilitiesextractableresultsshowedtotalphenols5timeshydrolyzedcompoundsdisplayedDPPHassaysMeanwhilealsoexhibitedinhibitionacarboseadditionmodelgastrointestinalusedreleasevaluesobviouslyincreasedgastricstageresultindicatedoftenoverlookeddiscardedpastpossessedAnti‐α‐glucosidasesimulatedNonextractablepolyphenolPersimmon

Similar Articles

Cited By