Usefulness of Home Overnight Pulse Oximetry in Patients with Suspected Sleep-Disordered Breathing.

Cristina Esteban-Amarilla, Silvia Martin-Bote, Antonio Jurado-Garcia, Ana Palomares-Muriana, Nuria Feu-Collado, Bernabe Jurado-Gamez
Author Information
  1. Cristina Esteban-Amarilla: Department of Respiratory Medicine, Pitie Salpetriere University Hospital, Paris, France. ORCID
  2. Silvia Martin-Bote: Department of Respiratory Medicine, Infanta Leonor University Hospital, Madrid, Spain. ORCID
  3. Antonio Jurado-Garcia: Physiotherapy Unit, San Juan de Dios Hospital, Cordoba, Spain. ORCID
  4. Ana Palomares-Muriana: Department of Respiratory Medicine, Hospital de Alta Resolución, Puente Genil, Cordoba, Spain. ORCID
  5. Nuria Feu-Collado: Department of Respiratory Medicine, Reina Sofía University Hospital, Córdoba, Spain. ORCID
  6. Bernabe Jurado-Gamez: Department of Respiratory Medicine, Reina Sofía University Hospital, Córdoba, Spain. ORCID

Abstract

Methods: Prospective study conducted in a university hospital. Subjects with a clinical suspicion of SAHS were included. All of them underwent home polygraphy and oximetry on the same night. A correlation was made between the apnea-hypopnea index (AHI) and the oximetry variables. The variable with the highest diagnostic value was calculated using the area under the curve (AUC), and the best cut-off point for discriminating between patients with SAHS and severe SAHS was identified.
Results: One hundred and four subjects were included; 73 were men (70%); mean age was 52 ± 10.1 years; body mass index was 30 ± 4.1, and AHI = 29 ± 23.2/h. A correlation was observed between the AHI and oximetry variables, particularly ODI3 ( = 0.850; < 0.001) and ODI4 ( = 0.912; < 0.001). For an AHI ≥ 10/h, the ODI3 had an AUC = 0.941 (95% confidence interval (CI) = 0.899-0.982) and the ODI4, an AUC = 0.984 (95% CI = 0.964-1), with the ODI4 having the best cut-off point (5.4/h). Similarly, for an AHI ≥ 30/h, the ODI4 had an AUC = 0.922 (95% CI = 0.859-0.986), with the best cut-off point being 10.5/h.
Conclusion: Nocturnal oximetry is useful for diagnosing and evaluating the severity of SAHS. The ODI4 variable was most closely correlated with AHI for both diagnosis.

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MeSH Term

Adult
Body Mass Index
Female
Humans
Male
Middle Aged
Oximetry
Polysomnography
Prospective Studies
Sleep Apnea Syndromes

Word Cloud

Created with Highcharts 10.0.0ODI4SAHSoximetryAHIbestcut-offpoint = 0AUC = 095%includedcorrelationindexvariablesvariable1ODI3<0001CI = 0Methods:ProspectivestudyconducteduniversityhospitalSubjectsclinicalsuspicionunderwenthomepolygraphynightmadeapnea-hypopneahighestdiagnosticvaluecalculatedusingareacurveAUCdiscriminatingpatientssevereidentifiedResults:Onehundredfoursubjects73men70%meanage52 ± 10yearsbodymass30 ± 4AHI = 29 ± 232/hobservedparticularly850912AHI ≥ 10/h941confidenceintervalCI899-0982984964-154/hSimilarlyAHI ≥ 30/h922859-0986105/hConclusion:NocturnalusefuldiagnosingevaluatingseveritycloselycorrelateddiagnosisUsefulnessHomeOvernightPulseOximetryPatientsSuspectedSleep-DisorderedBreathing

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