Change in Pull-Out Force during Resorption of Magnesium Compression Screws for Osteosynthesis of Mandibular Condylar Fractures.

Marcin Kozakiewicz
Author Information
  1. Marcin Kozakiewicz: Department of Maxillofacial Surgery, Medical University of Lodz, 113th S. Żeromskiego, 90-549 Lodz, Poland.

Abstract

BACKGROUND: Magnesium has been used as degradable fixation material for osteosynthesis, but it seems that mechanical strength is still a current issue in these fixations. The aim of this study was to evaluate the axial pull-out force of compression headless screws made of magnesium alloy during their resorption.
METHODS: The tests included screws made for osteosynthesis of the mandible head: 2.2 mm diameter magnesium alloy MgYREZr (42 screws) and 2.5 mm diameter polylactic-co-glycolic acid (PLGA) (42 pieces, control). The screws were resorbed in Sørensen's buffer for 2, 4, 8, 12, and 16 weeks, and force was measured as the screw was pulled out from the polyurethane block.
RESULTS: The force needed to pull the screw out was significantly higher for MgYREZr screws than for PLGA ones ( < 0.01). Within eight weeks, the pull-out force for MgYREZr significantly decreased to one third of its initial value ( < 0.01). The dynamics of this decrease were greater than those of the pull-out force for PLGA screws ( < 0.05). After these eight weeks, the values for metal and polymer screws equalized. It seems that the described reduction of force requires taking into account when using magnesium screws. This will provide more stable resorbable metallic osteosynthesis.

Keywords

References

  1. Materials (Basel). 2019 Apr 03;12(7): [PMID: 30987137]
  2. J Oral Maxillofac Surg. 2014 Feb;72(2):402.e1-13 [PMID: 24280169]
  3. J Oral Maxillofac Surg. 1999 Feb;57(2):113-8 [PMID: 9973116]
  4. Sci Rep. 2020 Oct 23;10(1):18193 [PMID: 33097806]
  5. Calcif Tissue Res. 1969;3(3):211-37 [PMID: 4894738]
  6. Arthroscopy. 1998 Oct;14(7):726-37 [PMID: 9788368]
  7. Biomaterials. 2018 Dec;185:383-392 [PMID: 30292588]
  8. J Clin Med. 2020 Sep 10;9(9): [PMID: 32927799]
  9. J Craniomaxillofac Surg. 2020 Apr;48(4):413-420 [PMID: 32127305]
  10. Br J Oral Maxillofac Surg. 2017 Jul;55(6):623-625 [PMID: 28460872]
  11. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Jul;94(1):5-14 [PMID: 12193886]
  12. Sci Rep. 2020 Oct 23;10(1):18143 [PMID: 33097757]
  13. Acta Biomater. 2014 Nov;10(11):4561-4573 [PMID: 25034646]
  14. Bioact Mater. 2020 Dec 02;6(6):1765-1776 [PMID: 33313453]
  15. Acta Biomater. 2017 Oct 15;62:434-445 [PMID: 28844965]
  16. Materials (Basel). 2020 Jun 10;13(11): [PMID: 32531885]
  17. Materials (Basel). 2020 Oct 16;13(20): [PMID: 33081398]
  18. J Oral Biol Craniofac Res. 2019 Apr-Jun;9(2):123-127 [PMID: 30815344]
  19. Sci Adv. 2020 Dec 11;6(50): [PMID: 33310851]
  20. Craniomaxillofac Trauma Reconstr. 2014 Mar;7(1):27-34 [PMID: 24624254]
  21. Clin Oral Investig. 2019 Nov;23(11):4059-4066 [PMID: 30891645]
  22. BMC Musculoskelet Disord. 2020 Nov 11;21(1):735 [PMID: 33176748]
  23. J Child Orthop. 2019 Jun 1;13(3):310-317 [PMID: 31312271]
  24. Oxid Med Cell Longev. 2018 Jun 14;2018:3714725 [PMID: 30013720]
  25. J Biomed Mater Res A. 2013 Jul;101(7):1898-906 [PMID: 23203562]
  26. PLoS One. 2020 Oct 8;15(10):e0240352 [PMID: 33031474]
  27. Front Immunol. 2019 Nov 08;10:2662 [PMID: 31781128]
  28. Injury. 2012 Jul;43(7):1159-65 [PMID: 22482931]
  29. Materials (Basel). 2019 Nov 30;12(23): [PMID: 31801225]
  30. Br J Oral Maxillofac Surg. 2016 Oct;54(8):872-877 [PMID: 27521271]
  31. Br J Oral Maxillofac Surg. 2018 Jan;56(1):74-76 [PMID: 29174002]
  32. Biomedicines. 2019 Feb 12;7(1): [PMID: 30759865]
  33. Biomedicines. 2020 Aug 21;8(9): [PMID: 32825692]
  34. Antimicrob Agents Chemother. 2014 Dec;58(12):7586-91 [PMID: 25288077]
  35. Rev Stomatol Chir Maxillofac. 1995;96(3):158-65 [PMID: 7644893]
  36. Mund Kiefer Gesichtschir. 2002 Mar;6(2):66-73 [PMID: 12017876]
  37. Arch Orthop Trauma Surg. 2009 Dec;129(12):1601-5 [PMID: 19911480]
  38. Materials (Basel). 2020 Sep 04;13(18): [PMID: 32899725]
  39. Pol Tyg Lek. 1970 Sep;25(37):1391-4 [PMID: 5470632]
  40. Br J Oral Maxillofac Surg. 2008 Sep;46(6):482-4 [PMID: 18499313]
  41. Biomaterials. 2014 Aug;35(24):6299-310 [PMID: 24816285]
  42. Bioact Mater. 2020 Nov 10;6(5):1341-1352 [PMID: 33210027]
  43. Acta Biomater. 2010 May;6(5):1869-77 [PMID: 19818422]
  44. Oral Implantol (Rome). 2017 Feb 14;9(Suppl 1/2016 to N 4/2016):107-111 [PMID: 28280540]
  45. Am J Orthod Dentofacial Orthop. 2012 Mar;141(3):279-288 [PMID: 22381488]
  46. J Oral Maxillofac Surg. 1993 Jun;51(6):666-70 [PMID: 8492205]
  47. Br J Oral Maxillofac Surg. 2010 Oct;48(7):520-6 [PMID: 19900741]
  48. J Craniomaxillofac Surg. 2015 May;43(4):452-61 [PMID: 25773375]
  49. Head Face Med. 2020 Oct 19;16(1):25 [PMID: 33076933]
  50. Arch Biochem Biophys. 2007 Feb 1;458(1):48-56 [PMID: 16712775]
  51. Biomaterials. 2000 Dec;21(23):2335-46 [PMID: 11055281]
  52. J Hand Surg Br. 2006 Apr;31(2):208-12 [PMID: 16361004]
  53. Biomaterials. 2006 Mar;27(9):1728-34 [PMID: 16246414]
  54. Eur J Orthop Surg Traumatol. 2015 Aug;25(6):997-1004 [PMID: 26084895]
  55. Biomaterials. 2000 Dec;21(24):2607-13 [PMID: 11071610]
  56. J Craniomaxillofac Surg. 2008 Jul;36(5):260-8 [PMID: 18328720]
  57. Sci Rep. 2016 Jun 07;6:27374 [PMID: 27271057]
  58. Materials (Basel). 2013 Nov 15;6(11):5258-5274 [PMID: 28788388]
  59. J Clin Med. 2019 Jan 21;8(1): [PMID: 30669680]
  60. Injury. 2010 Feb;41(2):179-83 [PMID: 19747678]
  61. J Oral Maxillofac Surg. 2006 Jan;64(1):31-9 [PMID: 16360854]
  62. Ann Transl Med. 2020 Nov;8(21):1419 [PMID: 33313164]
  63. Biomaterials. 2017 Jan;112:287-302 [PMID: 27770632]
  64. Materials (Basel). 2019 Jan 24;12(3): [PMID: 30682826]
  65. J Biomech Eng. 1996 Aug;118(3):391-8 [PMID: 8872262]
  66. Int J Periodontics Restorative Dent. 2013 May-Jun;33(3):355-63 [PMID: 23593629]

Grants

  1. 503-1-138-01-503-51-001-17, 503-1-138-01-503-51-001-18 and 503-1-138-01-503-51-001-19-00/Uniwersytet Medyczny w Lodzi

Word Cloud

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