OpenLB
Open Library of Bioscience
Advanced Search
Experimental and therapeutic medicine
Mar, 2021;21 (3): 266.

Kidney aging process and the management of the elderly patient with renal impairment (Review).

Raluca Ioana Papacocea, Delia Timofte, Maria-Daniela Tanasescu, Andra-Elena Balcangiu-Stroescu, Daniela Gabriela Balan, Adrian Tulin, Ovidiu Stiru, Ileana Adela Vacaroiu, Andrada Mihai, Cristian Constantin Popa, Cristina-Ileana Cosconel, Mihaly Enyedi, Daniela Miricescu, Laura Raducu, Dorin Ionescu
Author Information
  1. Raluca Ioana Papacocea: Discipline of Physiology, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  2. Delia Timofte: Department of Dialysis, Emergency University Hospital, 050098 Bucharest, Romania.
  3. Maria-Daniela Tanasescu: Department of Medical Semiology, Discipline of Internal Medicine I and Nephrology, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  4. Andra-Elena Balcangiu-Stroescu: Department of Dialysis, Emergency University Hospital, 050098 Bucharest, Romania.
  5. Daniela Gabriela Balan: Discipline of Physiology, Faculty of Dental Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  6. Adrian Tulin: Department of Anatomy, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  7. Ovidiu Stiru: Department of Cardiovascular Surgery, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  8. Ileana Adela Vacaroiu: Department of Nephrology and Dialysis, St. John Emergency Clinical Hospital, 042122 Bucharest, Romania.
  9. Andrada Mihai: Discipline of Diabetes, Nutrition and Metabolic Diseases-N. Paulescu National Institute, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  10. Cristian Constantin Popa: Department of Surgery, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  11. Cristina-Ileana Cosconel: Discipline of Foreign Languages, Faculty of Dental Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  12. Mihaly Enyedi: Department of Anatomy, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  13. Daniela Miricescu: Discipline of Biochemistry, Faculty of Dental Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  14. Laura Raducu: Discipline of Plastic and Reconstructive Surgery, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  15. Dorin Ionescu: Department of Dialysis, Emergency University Hospital, 050098 Bucharest, Romania.
PMID: 33603873 DOI: 10.3892/etm.2021.9697

Abstract

As life expectancy increases, a rise in the number of chronically ill patients is observed due to the aging population. Among the various diseases, chronic kidney disease is at present one of the main causes of morbidity and, due to its typical complications, it is also one of the most important causes of mortality in the general population. For these reasons, the understanding of the kidney aging process, its consequences and its adequate management are essential. The judicious use of certain types of drugs, the prevention of episodes of renal injury either by toxic mechanisms or by dehydration are important aspects and are part of the apropriate approach for elderly patients. The most effective treatment of various types of conditions with a negative impact on renal function and for which an increased incidence is known as we age should also be considered. Thus, in the case of elderly patients, in order to protect the kidneys, an integrative approach is recommended, one that includes both elements of prevention and the appropriate treatment of existing diseases.

Keywords

aging chronic kidney disease elderly patients morbidity renal aging

References

  1. Clin Interv Aging. 2018 Apr 26;13:757-772 [PMID: 29731617]
  2. Kidney Int Suppl (2011). 2014 Nov;4(1):75-78 [PMID: 26312154]
  3. Comput Struct Biotechnol J. 2019 Jun 18;17:721-729 [PMID: 31303976]
  4. J Hum Hypertens. 2010 Jan;24(1):1-8 [PMID: 19727125]
  5. Anesthesiol Clin. 2015 Sep;33(3):447-56 [PMID: 26315630]
  6. Medicine (Baltimore). 2016 Jul;95(30):e4203 [PMID: 27472690]
  7. Rev Endocr Metab Disord. 2017 Mar;18(1):41-47 [PMID: 27600582]
  8. Am J Kidney Dis. 2008 Feb;51(2):192-8 [PMID: 18215697]
  9. Ageing Res Rev. 2014 Mar;14:65-80 [PMID: 24548926]
  10. Medicina (Kaunas). 2019 Aug 03;55(8): [PMID: 31382651]
  11. Kidney Int Suppl (2011). 2013 Dec;3(4):368-371 [PMID: 25019021]
  12. J Am Soc Nephrol. 2017 Feb;28(2):407-420 [PMID: 28143966]
  13. Hypertension. 1997 Sep;30(3 Pt 2):677-81 [PMID: 9323004]
  14. Clin Interv Aging. 2014 Jan 15;9:191-9 [PMID: 24477220]
  15. Braz J Med Biol Res. 2011 Sep;44(9):905-13 [PMID: 21956533]
  16. J Am Soc Nephrol. 2017 Oct;28(10):2838-2844 [PMID: 28790143]
  17. Semin Nephrol. 2009 Sep;29(5):497-503 [PMID: 19751895]
  18. Exp Ther Med. 2020 Jul;20(1):97-102 [PMID: 32509000]
  19. Nat Rev Nephrol. 2015 May;11(5):264-76 [PMID: 25643664]
  20. Kidney Int Suppl. 2008 Dec;(111):S4-9 [PMID: 19034325]
  21. Adv Chronic Kidney Dis. 2010 Jul;17(4):302-7 [PMID: 20610357]
  22. Nefrologia. 2018 Jul - Aug;38(4):361-367 [PMID: 29627229]
  23. Kidney Dis (Basel). 2017 Jul;3(1):15-23 [PMID: 28785560]
  24. Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1329-F1335 [PMID: 30066587]
  25. Adv Chronic Kidney Dis. 2016 Jan;23(1):19-28 [PMID: 26709059]
  26. Eur J Nutr. 2019 Jun;58(Suppl 1):1-11 [PMID: 31254092]
  27. J Am Soc Nephrol. 2018 Aug;29(8):2157-2167 [PMID: 29980651]
  28. Prim Care. 2008 Jun;35(2):297-328, vi-vii [PMID: 18486717]
  29. J Am Geriatr Soc. 2013 Dec;61(12):2160-7 [PMID: 24479145]
Journal Article Review

Word Cloud

Created with Highcharts 10.0.0agingpatientsrenalelderlykidneyoneduepopulationvariousdiseaseschronicdiseasecausesmorbidityalsoimportantprocessmanagementtypespreventionapproachtreatmentlifeexpectancyincreasesrisenumberchronicallyillobservedAmongpresentmaintypicalcomplicationsmortalitygeneralreasonsunderstandingconsequencesadequateessentialjudicioususecertaindrugsepisodesinjuryeithertoxicmechanismsdehydrationaspectspartapropriateeffectiveconditionsnegativeimpactfunctionincreasedincidenceknownageconsideredThuscaseorderprotectkidneysintegrativerecommendedincludeselementsappropriateexistingKidneypatientimpairmentReview

Similar Articles

Cited By