Advances in stimulated Raman scattering imaging for tissues and animals.

Lingyan Shi, Anthony A Fung, Andy Zhou
Author Information
  1. Lingyan Shi: Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.
  2. Anthony A Fung: Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.
  3. Andy Zhou: Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.

Abstract

Stimulated Raman scattering (SRS) microscopy has emerged in the last decade as a powerful optical imaging technology with high chemical selectivity, speed, and subcellular resolution. Since the invention of SRS microscopy, it has been extensively employed in life science to study composition, structure, metabolism, development, and disease in biological systems. Applications of SRS in research and the clinic have generated new insights in many fields including neurobiology, tumor biology, developmental biology, metabolomics, pharmacokinetics, and more. Herein we review the advances and applications of SRS microscopy imaging in tissues and animals, as well as envision future applications and development of SRS imaging in life science and medicine.

Keywords

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Grants

  1. U54 CA132378/NCI NIH HHS

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