OpenLB
Open Library of Bioscience
Advanced Search
Bio-protocol
Jun 20, 2019;9 (12): e3263.

Determining Oxidative Damage by Lipid Peroxidation Assay in Rat Serum.

Qian Tang, Yu-Wen Su, Cory J Xian
Author Information
  1. Qian Tang: School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5001, Australia.
  2. Yu-Wen Su: School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5001, Australia.
  3. Cory J Xian: School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5001, Australia.
PMID: 33654783 DOI: 10.21769/BioProtoc.3263

Abstract

It has been well-established that malondialdehyde (MDA), which is generated during the process of lipid peroxidation, is a commonly known biomarker for oxidative stress. Therefore, the serum levels of MDA are detected by using the lipid peroxidation assay with commercially available kit to determine the induction of oxidative stress in Rat models.

Keywords

Lipid peroxidation MDA-TBA adduct Malondialdehyde Oxidative stress Serum Thiobarbituric acid

References

  1. Oxid Med Cell Longev. 2017;2017:6501046 [PMID: 28698768]
  2. J Bone Miner Res. 2019 Feb;34(2):310-326 [PMID: 30395366]
Journal Article

Word Cloud

Created with Highcharts 10.0.0peroxidationstressMDAlipidoxidativeOxidativeLipidSerumwell-establishedmalondialdehydegeneratedprocesscommonlyknownbiomarkerThereforeserumlevelsdetectedusingassaycommerciallyavailablekitdetermineinductionratmodelsDeterminingDamagePeroxidationAssayRatMDA-TBAadductMalondialdehydeThiobarbituricacid

Similar Articles

Cited By (12)