Elderly musculoskeletal disease burden in Karachi, Pakistan: Associations and implications for developing countries.

Saniya Sabzwari, Zafar Fatmi, Adeel Ahmed Khan
Author Information
  1. Saniya Sabzwari: Aga Khan University Hospital Karachi Pakistan. ORCID
  2. Zafar Fatmi: Aga Khan University Hospital Karachi Pakistan.
  3. Adeel Ahmed Khan: Saudi Board Program of Preventive Medicine Mecca Pakistan.

Abstract

OBJECTIVE: The global rise in the older population has increased the rates of osteoporosis and osteoarthritis, conditions that impact mobility and functionality. There is limited data on musculoskeletal disease in older populations residing in developing countries.
METHODS: A community-based study using multistage cluster random sampling of older individuals was conducted in Karachi. Predefined criteria were used for osteoporosis and osteoarthritis. Gait assessment was performed.
RESULTS: More than half of the participants were females and 53% reported illiteracy. Around 30% had osteoporosis and two-thirds had osteoarthritis. Multivariate analysis showed associations of female sex, Pashtun ethnicity, illiteracy, and hypertension with the combined variable of osteoporosis and osteoarthritis.
CONCLUSIONS: The prevalence of osteoarthritis was higher than in other regional studies. Presence of both osteoporosis and osteoarthritis increased the risk of certain geriatric syndromes. High rates of musculoskeletal morbidity are seen in the elderly in Pakistan. Measures at a health-system level are required for better outcomes in older adults.

Keywords

References

  1. Health Educ Res. 2012 Dec;27(6):947-60 [PMID: 22752153]
  2. BMC Musculoskelet Disord. 2012 May 29;13:82 [PMID: 22642899]
  3. Eur J Public Health. 2016 Feb;26(1):192-8 [PMID: 26105959]
  4. BMC Womens Health. 2015 Oct 12;15:83 [PMID: 26458880]
  5. Aging Med (Milton). 2020 Dec 22;4(1):19-25 [PMID: 33738376]
  6. PLoS One. 2014 Mar 05;9(3):e90813 [PMID: 24599391]
  7. Arthritis Rheumatol. 2014 Mar;66(3):622-36 [PMID: 24574223]
  8. Nutrients. 2014 Sep 12;6(9):3601-23 [PMID: 25221975]
  9. Br J Rheumatol. 1998 May;37(5):491-5 [PMID: 9651074]
  10. Nat Rev Rheumatol. 2012 Dec;8(12):729-37 [PMID: 22907293]
  11. Int J Rheum Dis. 2011 May;14(2):113-21 [PMID: 21518309]
  12. Osteoporos Int. 2009 Dec;20(12):2049-53 [PMID: 19343468]
  13. BMJ. 2003 Mar 1;326(7387):469 [PMID: 12609940]
  14. Medicine (Baltimore). 2017 Aug;96(32):e7584 [PMID: 28796041]
  15. Osteoporos Int. 2015 Aug;26(8):2203-8 [PMID: 25994904]
  16. Indian J Endocrinol Metab. 2014 Jul;18(4):449-54 [PMID: 25143898]
  17. PLoS One. 2019 Jun 27;14(6):e0218872 [PMID: 31247025]
  18. Practitioner. 2015 Dec;259(1788):15-9, 2 [PMID: 26882774]
  19. J Obstet Gynaecol Can. 2009 May;31(5):434-9 [PMID: 19604424]
  20. J Am Geriatr Soc. 2000 Jul;48(7):721-5 [PMID: 10894308]
  21. Bone. 2006 Feb;38(2 Suppl 1):S4-9 [PMID: 16455317]
  22. Ann Rheum Dis. 2017 Aug;76(8):1365-1373 [PMID: 28209629]
  23. J Rheumatol. 2005 Feb;32(2):348-53 [PMID: 15693098]
  24. Eur J Rheumatol. 2017 Mar;4(1):46-56 [PMID: 28293453]
  25. J Rheumatol. 2009 Mar;36(3):614-22 [PMID: 19208598]
  26. J Gerontol A Biol Sci Med Sci. 2013 Oct;68(10):1243-51 [PMID: 23902935]
  27. Rheumatol Int. 2011 Jul;31(7):849-55 [PMID: 21331574]
  28. Arch Osteoporos. 2012;7:275-82 [PMID: 23152063]

Word Cloud

Created with Highcharts 10.0.0osteoarthritisosteoporosisoldermusculoskeletalincreasedratesdiseasedevelopingcountriesKarachiilliteracyOBJECTIVE:globalrisepopulationconditionsimpactmobilityfunctionalitylimiteddatapopulationsresidingMETHODS:community-basedstudyusingmultistageclusterrandomsamplingindividualsconductedPredefinedcriteriausedGaitassessmentperformedRESULTS:halfparticipantsfemales53%reportedAround30%two-thirdsMultivariateanalysisshowedassociationsfemalesexPashtunethnicityhypertensioncombinedvariableCONCLUSIONS:prevalencehigherregionalstudiesPresenceriskcertaingeriatricsyndromesHighmorbidityseenelderlyPakistanMeasureshealth-systemlevelrequiredbetteroutcomesadultsElderlyburdenPakistan:Associationsimplicationscommunity

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