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Frontiers in endocrinology
2021;12 661877.

Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes.

Md Kamruzzaman, Michael Horowitz, Karen L Jones, Chinmay S Marathe
Author Information
  1. Md Kamruzzaman: Department of Applied Nutrition and Food Technology, Islamic University, Kushtia, Bangladesh.
  2. Michael Horowitz: Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.
  3. Karen L Jones: Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.
  4. Chinmay S Marathe: Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.
PMID: 33897622 DOI: 10.3389/fendo.2021.661877

Abstract

Postprandial glycemic control is an important target for optimal type 2 diabetes management, but is often difficult to achieve. The gastrointestinal tract plays a major role in modulating postprandial glycaemia in both health and diabetes. The various strategies that have been proposed to modulate gastrointestinal function, particularly by slowing gastric emptying and/or stimulating incretin hormone GLP-1, are summarized in this review.

Keywords

GLP-1 receptor agonist gastric emptying incretin hormones postprandial glucose (PPG) type 2 diabetes

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MeSH Term

Blood Glucose
Diabetes Mellitus, Type 2
Gastric Emptying
Glucagon-Like Peptide 1
Humans
Incretins
Postprandial Period

Chemicals

Blood Glucose
Incretins
Glucagon-Like Peptide 1
Journal Article Review
Article has an altmetric score of 44

Word Cloud

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