[Role of cefditoren in the treatment of community skin and soft tissue infections: revisiting the evidence].

M D Cabañero-Navalón, V García-Bustos, M Salavert Lletí
Author Information
  1. M Salavert Lletí: Miguel Salavert Lletí, Unidad de Enfermedades Infecciosas. Área Clínica Médica. Hospital Universitario y Politécnico La Fe, Valencia, Spain. Salavert_mig@gva.es.

Abstract

Cefditoren pivoxil is a third-generation oral cephalosporin with extended spectrum against Gram-negative, Gram-positive, and several anaerobic microorganisms, including those frequently implicated in skin and soft tissue infections (SSTI). Despite the fact that there are no approved breakpoint criteria for cefditoren susceptibility, many pharmacokinetic and pharmacodynamic studies reassert cefditoren as a good oral antibiotic for the treatment of SSTI. Regarding patients with SSTI, including those infections caused by Staphylococcus aureus y Streptococcus pyogenes, cefditoren showed high cure rates when compared to other oral cephalosporins.

Keywords

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MeSH Term

Anti-Bacterial Agents
Cephalosporins
Humans
Soft Tissue Infections

Chemicals

Anti-Bacterial Agents
Cephalosporins
cefditoren

Word Cloud

Created with Highcharts 10.0.0cefditorenoralskinsofttissueinfectionsSSTICefditorenpivoxilincludingtreatmentcephalosporinsthird-generationcephalosporinextendedspectrumGram-negativeGram-positiveseveralanaerobicmicroorganismsfrequentlyimplicatedDespitefactapprovedbreakpointcriteriasusceptibilitymanypharmacokineticpharmacodynamicstudiesreassertgoodantibioticRegardingpatientscausedStaphylococcusaureusyStreptococcuspyogenesshowedhighcureratescompared[Rolecommunityinfections:revisitingevidence]

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