Relationship between high CRP and cytokines in Saudi old people with dental caries in alkharj Region, Saudi Arabia.
Arwa F Alanazi, Awwad Alenezy, Amna Alotiby, Talat Bukhari, Wael Alturaiki, Abdulkarim S BinShaya, Hisham Ali Waggiallah, Harbi W, Kahtani Y, Majli K, Amani F Alanazi, Faris Q B Alenzi
Author Information
Arwa F Alanazi: Dept of Dentistry, Riyadh Alm University, Riyadh, Saudi Arabia.
Awwad Alenezy: Dept of Family and Community Medicine, College of Medicine, NBU, Arar, Saudi Arabia.
Amna Alotiby: Dept of Immunology, College of Medicine, Um Qura University, Makka, Saudi Arabia.
Talat Bukhari: Dept of Immunology, College of Medicine, Um Qura University, Makka, Saudi Arabia.
Wael Alturaiki: Dept of Med Lab Sci, College of Appl Med Sci, Majmma University, Saudi Arabia.
Abdulkarim S BinShaya: Dept of Med Lab Sci, College of Appl Med Sci, Prince Sattam University, Alkharj, Saudi Arabia.
Hisham Ali Waggiallah: Dept of Med Lab Sci, College of Appl Med Sci, Prince Sattam University, Alkharj, Saudi Arabia.
Harbi W: Dept of Med Lab Sci, College of Appl Med Sci, Prince Sattam University, Alkharj, Saudi Arabia.
Kahtani Y: Dept of Med Lab Sci, College of Appl Med Sci, Prince Sattam University, Alkharj, Saudi Arabia.
Majli K: Dept of Med Lab Sci, College of Appl Med Sci, Prince Sattam University, Alkharj, Saudi Arabia.
Amani F Alanazi: Dept of RT, Al-Marafa University, Riyadh, Saudi Arabia.
Faris Q B Alenzi: Dept of Med Lab Sci, College of Appl Med Sci, Prince Sattam University, Alkharj, Saudi Arabia.
OBJECTIVE: Dental caries is one of the most common problems of the oral cavity which is frequently observed in older people. The aim of this study is to evaluate serum C-reactive proteins (CRP) levels and to identify the correlation between dental caries and CRP levels. METHODOLOGY: The study included 12 aged patients with an average age of 65-years; the patients were diagnosed with dental caries and did not have clinical history of heart diseases, rheumatoid arthritis or any other infection. The control group consisted of 10 healthy donors with an average age of 60-years. The CRP level of positive samples was measured by using CRP Enzyme-linked immunosorbent assay-ELISA Kit. RESULTS: The currents study showed that only 5 out of 12 patients were CRP positive. CONCLUSIONS: Because of study limitations, it is early to conclude of close relationship between serum CRP and dental caries from the findings of this study; however, this study will give a clearer picture to understand the relationship between serum CRP, inflammatory cytokines and dental caries.
