[Epidemiological investigation and analysis of etiological characteristics of infection on 3 067 hospitalized pediatric patients with burns].

C Zhang, Y Peng, X Q Luo, Q M Li, Z C Yang, Y Chen, Y Z Peng, Y X Zhang, Y L Gong
Author Information
  1. C Zhang: State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.
  2. Y Peng: Department of Plastic and Reconstructive Surgery, Shanghai ninth People's Hospital, Shanghai Jiao Tong University School of Medical, Shanghai 200011, China.
  3. X Q Luo: State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.
  4. Q M Li: State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.
  5. Z C Yang: Department of Reconstructive Surgery , the Second Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400037, China.
  6. Y Chen: State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.
  7. Y Z Peng: State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.
  8. Y X Zhang: Department of Plastic and Reconstructive Surgery, Shanghai ninth People's Hospital, Shanghai Jiao Tong University School of Medical, Shanghai 200011, China.
  9. Y L Gong: State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.

Abstract

To investigate the epidemiological characteristics and etiological distribution of infection on 3 067 hospitalized pediatric patients with burns, and explore the prevention and treatment strategy of pediatric burns. A cross-sectional survey was conducted. An analysis was performed on the data of 3 067 hospitalized pediatric patients with burns who met the inclusion criteria and were admitted to the First Affiliated Hospital of Army Medical University (the Third Military Medical University) from January 2012 to December 2020, including gender, age, causative factors, locations and severities of burns, seasons of accidents, and the type, source of tissue or body fluid, and drug resistance of pathogenic bacteria. API bacterial identification batten and automatic microbial identification system were applied for pathogen identification. Drug sensitivities of top 3 consistent ratio pathogen identifed were tested with minimum inhibitory concentration and disk diffusion method. WHONET 5.6 software was applied to analyze the data. There were 3 067 hospitalized pediatric patients with burns, including 1 768 boys and 1 299 girls. The majority of pediatric burn patients were >1 and ���4 years, accounting for 72.9% (2 236/3 067), and the minority of pediatric burn patients were >8 and ���12 years, accounting for 4.9% (150/3 067). Moderate burns and severe burns of pediatric burn patients accounted for the majority parts, and the proportions of the two were close. The top cause of pediatric burns was scald, accounting for 81.6% (2504/3 067). Extremities were the most common burn sites in that of entire 3 254. The most pediatric burns occurred in winter, accounting for 29.4% (903/3 067). A total of 1 018 strains of pathogenic bacteria were collected from pediatric burn patients, all of which were non-repeated isolates. The pathogens with top five consistent ratio were , , , , and , among which ranked the first every year. The pathogens were mainly isolated from the wound exudate, accounting for 81.34% (828/1 018). from 2012 to 2020 showed no resistance to vancomycin, linezolid or teicoplanin while isolated in 2019 was 100% resistant to macrolides, penicillin, aminoglycosides, and quinolones. was not resistant to polymyxin B. showed a high rate of drug resistance to most antibiotics. Among the pediatric burn patients admitted to the First Affiliated Hospital of Army Medical University (the Third Military Medical University) from 2012 to 2020, the majority are male children aged >1 and ���4 years with moderate burns. Scalds are the leading cause; and extremities are the common burn sites; and the most pediatric burns occurre in winter. from wound exudate is the primary pathogen of burn wound infections in pediatric patients.

References

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Grants

  1. 81772073, 81571896/General Program of National Natural Science Foundation of China

MeSH Term

Acinetobacter baumannii
Anti-Bacterial Agents
Burns
Child
Cross-Sectional Studies
Drug Resistance, Bacterial
Female
Humans
Male
Microbial Sensitivity Tests

Chemicals

Anti-Bacterial Agents

Word Cloud

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