Prevalence of oral HPV infection in unvaccinated young adults in Brazil.
Augusto Bacelo Bidinotto, Natália Luiza Kops, Marina Bessel, Ana Goretti Kalume Maranhão, Flávia Moreno, Gérson Fernando Mendes Pereira, Luísa Lina Villa, Eliana Márcia Wendland, POP-Brazil Study Group
Author Information
Augusto Bacelo Bidinotto: Hospital Moinhos de Vento, Porto Alegre, Brazil.
Natália Luiza Kops: Hospital Moinhos de Vento, Porto Alegre, Brazil.
Marina Bessel: Hospital Moinhos de Vento, Porto Alegre, Brazil.
Ana Goretti Kalume Maranhão: National Immunization Program, Ministry of Health, Brasília, Brazil.
Flávia Moreno: Department of Chronic Conditions and Sexually Transmitted Infections, Ministry of Health, Brasília, Brazil.
Gérson Fernando Mendes Pereira: Department of Chronic Conditions and Sexually Transmitted Infections, Ministry of Health, Brasília, Brazil.
Luísa Lina Villa: Faculty of Medicine, University of São Paulo and Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, Brazil.
Eliana Márcia Wendland: Hospital Moinhos de Vento, Porto Alegre, Brazil; Department of Community Health, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil. Electronic address: eliana.wendland@hmv.org.br.
OBJECTIVES: This study aimed to report the national prevalence of oralHPV infection among unvaccinated women and men aged 16-25 years who utilized the public primary care services. METHODS: POP-Brazil is a cross-sectional, multicentric, nationwide survey conducted between September 2016 and November 2017. Recruitment was based in 119 public primary care practices in 26 state capitals and the Federal District of Brazil. Trained health professionals conducted face-to-face interviews. oral samples were collected with mouthwash and gargle cycles. Genotyping was performed using the Roche PCR-based linear array genotyping test. Sampling weights by sex and age were applied. RESULTS: Valid oralHPV samples were collected from 5071 (96.88%) participants; 4005 women and 1066 men. Mean participant age was 21.63 years. Overall HPV prevalence was 1.69% (n = 73, 95% CI 1.05-2.32). Thirty individuals presented at least one high-risk HPV type [0.57% (95% CI, 0.29-0.85)]. There were no associations between age, sex, sociodemographic characteristics, drug use or sexual behavior and oralHPV prevalence. CONCLUSION: The prevalence of oralHPV infection in Brazilian teenagers and young adults is low, with no sociodemographic or behavioral correlates.
