A Multilevel Intervention to Increase HPV Vaccination among Asian American Adolescents.
Grace X Ma, Lin Zhu, Yin Tan, Shumenghui Zhai, Timmy R Lin, Cristina Zambrano, Philip Siu, Sarah Lai, Min Qi Wang
Author Information
Grace X Ma: Center for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA. grace.ma@temple.edu. ORCID
Lin Zhu: Center for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA.
Yin Tan: Center for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA.
Shumenghui Zhai: Center for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA.
Timmy R Lin: Center for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA.
Cristina Zambrano: Hunter College Center for Cancer Health Disparities Research, 695 Park Avenue, New York, NY, 10065, USA.
Philip Siu: Greater Philadelphia Health Action, Inc., 432 N 6th St, Philadelphia, PA, 19123, USA.
Sarah Lai: Greater Philadelphia Health Action, Inc., 432 N 6th St, Philadelphia, PA, 19123, USA.
Min Qi Wang: School of Public Health, University of Maryland, 4200 Valley Dr, College Park, MD, 20742, USA.
Human papillomavirus (HPV) is the most common sexually transmitted infection in the US. HPV vaccine is a viable source of prevention against high-risk strains that are likely to cause cancer. However, particularly among racial and ethnic minorities such as Chinese Americans, HPV vaccination rates are suboptimal. The goal of this study was to evaluate the effect of a culturally tailored intervention on HPV vaccine uptake in Chinese Americans. We designed and implemented a multilevel longitudinal pilot study to examine the efficacy of the HPV intervention among Chinese American parents/guardians. We recruited 180 participants from federally qualified health center and community-based clinics that serve predominantly low-income Chinese Americans in Philadelphia. Participants were randomized into an intervention group (n = 110) or a control group (n = 70). The intervention group received an HPV specific intervention, while the control group received a general health intervention. The primary outcome was medical record-confirmed receipt of first shot and completion of HPV vaccine within six months of receiving the interventions. Repeated measure ANOVA was utilized to examine the intervention effect on knowledge between intervention and control groups. Knowledge differed significantly, with participants in the intervention group demonstrating the greatest improvement following the intervention. A multivariable logistic regression was used to examine the association between HPV vaccine initiation and study group assignment. There was a significant effect of provider recommendation, parent's gender, and health insurance status on HPV vaccine uptake. This study demonstrated positive impact of a culturally tailored intervention on HPV vaccination uptake among Chinese Americans.
