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European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
10, 2021;30 (10): 3115-3127.

Trends of epidemiological characteristics of traumatic spinal cord injury in China, 2009-2018.

Dingjun Hao, Jinpeng Du, Liang Yan, Baorong He, Xiao Qi, Shicheng Yu, Jiaojiao Zhang, Wenjing Zheng, Rongqiang Zhang, Da-Geng Huang, Junsong Yang, Ming Zhu, Jiawei Ouyang, He Zhao, Keyuan Ding, Haodong Shi, Yang Cao, Ying Zhang, Qinghua Tang, Yuan Liu, Zilong Zhang, Yuhang Wang, Ye Tian, Hao Chen, Lulu Bai, Heng Li, Chenchen Mu, Youhan Wang, Xiaohui Wang, Chao Jiang, Jianhua Lin, Bin Lin, Shunwu Fan, Lin Nie, Jiefu Song, Xun Ma, Zengwu Shao, Yanzheng Gao, Zhong Guan, Yueming Song, Weihu Ma, Qixin Chen
Author Information
  1. Dingjun Hao: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China. hhyyhdj@126.com. ORCID
  2. Jinpeng Du: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  3. Liang Yan: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  4. Baorong He: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  5. Xiao Qi: Office of Epidemiology, Chinese Center for Disease Control and Prevention, Beijing, China.
  6. Shicheng Yu: Office of Epidemiology, Chinese Center for Disease Control and Prevention, Beijing, China.
  7. Jiaojiao Zhang: Office of Epidemiology, Chinese Center for Disease Control and Prevention, Beijing, China.
  8. Wenjing Zheng: Office of Epidemiology, Chinese Center for Disease Control and Prevention, Beijing, China.
  9. Rongqiang Zhang: Office of Epidemiology, School of Public Health, Shaanxi University of Traditional Chinese Medicine, Xianyang, China.
  10. Da-Geng Huang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  11. Junsong Yang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  12. Ming Zhu: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  13. Jiawei Ouyang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  14. He Zhao: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  15. Keyuan Ding: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  16. Haodong Shi: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  17. Yang Cao: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  18. Ying Zhang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  19. Qinghua Tang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  20. Yuan Liu: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  21. Zilong Zhang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  22. Yuhang Wang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  23. Ye Tian: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  24. Hao Chen: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  25. Lulu Bai: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  26. Heng Li: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  27. Chenchen Mu: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  28. Youhan Wang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  29. Xiaohui Wang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  30. Chao Jiang: Department of Spine Surgery, Honghui Hospital, Xi'an Jiao Tong University, Youyidong Road, Xi'an, 710000, Shaanxi Province, China.
  31. Jianhua Lin: Department of Spine Surgery, The First Affiliated Hospital of Fujian Medical University, Fujian, China.
  32. Bin Lin: Department of Orthopaedic, The No. 909 Hospital of the People's Liberation Army, Zhangzhou, China.
  33. Shunwu Fan: Department of Orthopaedic, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Zhejiang, China.
  34. Lin Nie: Department of Spine Surgery, Qilu Hospital of Shandong University, Shandong, China.
  35. Jiefu Song: Department of Orthopaedic, Shanxi Provincial People's Hospital, Taiyuan, China.
  36. Xun Ma: Department of Orthopaedic, Shanxi Bethune Hospital, Taiyuan, China.
  37. Zengwu Shao: Department of Orthopaedic, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
  38. Yanzheng Gao: Department of Orthopaedic, Henan Provincial People's Hospital, Zhengzhou, China.
  39. Zhong Guan: Department of Spine Surgery, Qinghai University Affiliated Hospital, Xining, China.
  40. Yueming Song: Department of Spine Surgery, West China Hospital of Sichuan University, Chengdu, China.
  41. Weihu Ma: Department of Spine Surgery, Ningbo No. 6 Hospital, Ningbo, China.
  42. Qixin Chen: Department of Orthopaedic, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
PMID: 34392419 DOI: 10.1007/s00586-021-06957-3

Abstract

OBJECTIVE: We focus on providing the first comprehensive national dataset on the incidence, injury aetiology and mortality of TSCI in China.
METHODS: A multi-stage stratified cluster sampling method was used. We included TSCI cases from all hospitals in three regions, nine provinces and 27 cities in China via search of electronic medical records and retrospectively analysed the characteristics of TSCI in China from 2009 to 2018. We estimated the incidence of TSCI in the total population and subgroups.
RESULTS: There were 5954 actual cases in 2009, corresponding to a total estimated TSCI incidence of 45.1 cases per million population (95% CI, 44.0-46.3). There were 10,074 actual cases in 2018, corresponding to a total estimated TSCI incidence of 66.5 cases per million population (95% CI, 65.2-67.8) (P < 0.001; annual average percentage change (AAPC), 4.4%). From 2009 to 2018, the incidence of almost all sex/age groups showed an increasing trend over time (P < 0.001; AAPC, 0.7-8.8%). The elderly population (aged 65-74) displayed the highest incidence of TSCI (with an average annual incidence of 127.1 cases per million [95% CI, 119.8-134.3]).
CONCLUSIONS: The TSCI incidence increased significantly from 2009 to 2018. The incidence in the elderly populations was consistently high and continues to increase over time. The mortality of TSCI patients in hospitals is relatively low and continues to decrease each year, but elderly individuals remain at a high risk of hospital death.

Keywords

China Epidemiology Incidence Mortality Spinal cord injury

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MeSH Term

Aged
China
Humans
Incidence
Research Design
Retrospective Studies
Spinal Cord Injuries
Journal Article Research Support, Non-U.S. Gov't
Article has an altmetric score of 1

Word Cloud

Created with Highcharts 10.0.0incidenceTSCIcasesChina20092018populationinjuryestimatedtotalpermillionCIelderlymortalityhospitalscharacteristicsactualcorresponding195%P < 0001annualaverageAAPCtimehighcontinuescordOBJECTIVE:focusprovidingfirstcomprehensivenationaldatasetaetiologyMETHODS:multi-stagestratifiedclustersamplingmethodusedincludedthreeregionsnineprovinces27citiesviasearchelectronicmedicalrecordsretrospectivelyanalysedsubgroupsRESULTS:595445440-46310074665652-678percentagechange44%almostsex/agegroupsshowedincreasingtrend07-88%aged65-74displayedhighest127[95%1198-1343]CONCLUSIONS:increasedsignificantlypopulationsconsistentlyincreasepatientsrelativelylowdecreaseyearindividualsremainriskhospitaldeathTrendsepidemiologicaltraumaticspinal2009-2018EpidemiologyIncidenceMortalitySpinal

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