Addressing the gender pain gap.

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John M Dawes, David L Bennett

Author Information

John M Dawes: Neural Injury Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
David L Bennett: Neural Injury Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK. Electronic address: david.bennett@ndcn.ox.ac.uk.

PMID: 34473950 DOI: 10.1016/j.neuron.2021.08.006

Chronic pain is more common in women, however, our understanding of sex-specific differences in pain mechanisms is rudimentary. In this issue of Neuron, Luo et al., (2021) delineate a novel sex-specific neuro-immune pathway contributing to enhanced mechanical pain in females.

IL-17A IL-23 TRPV1 mechanical pain neuroimmune pain sex differences

202747/Z/16/Z/Wellcome Trust
MR/T020113/1/Medical Research Council
MR/V003534/1/Medical Research Council
MR/W002388/1/Medical Research Council

Chronic Pain

Female

Humans

Male

Neurons

Sex Characteristics

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