Polypharmacy and Potentially Inappropriate Medication Use in Older Blacks with Diabetes Mellitus Presenting to the Emergency Department.

Ginah Nightingale, Emily M Scopelliti, Robin Casten, Monica Woloshin, Shu Xiao, Megan Kelley, Anna Marie Chang, Judd E Hollander, Benjamin E Leiby, Andrew M Peterson, Laura T Pizzi, Kristin L Rising, Neva White, Barry Rovner
Author Information
  1. Ginah Nightingale: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA. ORCID
  2. Emily M Scopelliti: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  3. Robin Casten: Department of Psychiatry and Human Behavior, Sidney Kimmel Medical College, 6559Thomas Jefferson University, Philadelphia, PA, USA.
  4. Monica Woloshin: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  5. Shu Xiao: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  6. Megan Kelley: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  7. Anna Marie Chang: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  8. Judd E Hollander: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  9. Benjamin E Leiby: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  10. Andrew M Peterson: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  11. Laura T Pizzi: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  12. Kristin L Rising: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  13. Neva White: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.
  14. Barry Rovner: Department of Pharmacy Practice, Jefferson College of Pharmacy, 114062Thomas Jefferson University, Philadelphia, PA, USA.

Abstract

Medication-related problems in older Blacks with diabetes mellitus (DM) are not well established. To describe the frequency of medication-related problems in older Blacks with DM presenting to the emergency department (ED). The study was a cross-sectional analysis of baseline data from a randomized controlled trial evaluating Blacks aged ≥60 years of age presenting to the ED. Polypharmacy, potentially inappropriate medication (PIM) use, and anticholinergic score were evaluated. Of 168 patients (median age = 68, range 60-92), most ( = 164, 98%) were taking ≥5 medications, and 67 (39.9%) were taking a PIM. A majority ( = 124, 74%) were taking a medication with an anticholinergic score ≥1. Number of medications was correlated with number of PIMs ( = .22, = .004) and anticholinergic score ( = .50, < .001). Polypharmacy and PIM use was common in older Blacks with DM.

Keywords

MeSH Term

Aged
Cholinergic Antagonists
Cross-Sectional Studies
Diabetes Mellitus
Emergency Service, Hospital
Humans
Inappropriate Prescribing
Polypharmacy
Potentially Inappropriate Medication List

Chemicals

Cholinergic Antagonists

Word Cloud

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