- Renee Garett: ElevateU, Irvine, CA, USA.
- Sean D Young: Department of Emergency Medicine, University of California, Irvine, CA 92697, USA.
Although rates of vaccination have increased worldwide, the rise in nonmedical exemptions for vaccination may have caused a resurgence of childhood vaccine-preventable diseases. Vaccine hesitancy plays an important role in the decreasing rates of vaccination and is considered by the World Health Organization as a top ten global threat to public health. Online vaccine misinformation is present in news outlets, websites, and social media, and its rapid and extensive dissemination is aided by artificial intelligence (AI). In combating online misinformation, public health experts, the medical community, and lay vaccination advocates can correct false statements using language that appeal to those who are undecided about vaccination. As the gatekeepers to online information, they can implement and enforce policy that limits or bans vaccine misinformation on their platforms. AI tools might also be used to address misinformation, but more research is needed before implementing this approach more broadly in health policy. This commentary examines the role that different online platforms appear to be playing in the spread of misinformation about vaccines. We also discuss the implications of online misinformation on attitudes about COVID-19 vaccine uptake and provide suggestions for ways to combat online misinformation.