Epidemiology and incidence of HPV-related cancers of the head and neck.

Benjamin R Roman, Abraham Aragones
Author Information
  1. Benjamin R Roman: Departments of Surgery and Strategy & Innovation, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  2. Abraham Aragones: Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Abstract

Globally, 4.5% of cancers are due to the human papillomavirus (HPV). In the United States, 80 million people are infected with HPV, and the incidence of HPV oropharyngeal cancer has surpassed HPV cervical cancer. The highest burden of oropharyngeal cancer is seen in middle-aged and increasingly older White men. HPV vaccination promises to change the epidemiology of this disease, but HPV vaccination rates remain too low today to reduce disease transmission.

Keywords

References

  1. JNCI Cancer Spectr. 2019 Jan 07;2(4):pky045 [PMID: 31360870]
  2. MMWR Morb Mortal Wkly Rep. 2020 Aug 21;69(33):1109-1116 [PMID: 32817598]
  3. Emerg Infect Dis. 2014 May;20(5):822-8 [PMID: 24751181]
  4. J Clin Oncol. 2015 Oct 10;33(29):3235-42 [PMID: 26351338]
  5. J Clin Oncol. 2011 Nov 10;29(32):4294-301 [PMID: 21969503]
  6. Cancer Epidemiol Biomarkers Prev. 2019 Oct;28(10):1660-1667 [PMID: 31358520]
  7. J Gen Virol. 2017 Apr;98(4):519-526 [PMID: 28150575]
  8. J Clin Oncol. 2019 Jun 20;37(18):1538-1546 [PMID: 31026209]
  9. JAMA. 2019 Sep 10;322(10):977-979 [PMID: 31503300]
  10. Lancet. 2019 Aug 10;394(10197):497-509 [PMID: 31255301]
  11. JAMA Oncol. 2021 Oct 1;7(10):e212907 [PMID: 34473210]

Grants

  1. P30 CA008748/NCI NIH HHS
  2. P30CA008748/NCI NIH HHS

MeSH Term

Head and Neck Neoplasms
Humans
Incidence
Papillomaviridae
Papillomavirus Infections