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Clinical immunology (Orlando, Fla.)
11, 2021;232 108849.

A hitchhiker's guide through the COVID-19 galaxy.

Susanna Felsenstein, Andreas Otto Reiff
Author Information
  1. Susanna Felsenstein: University of Liverpool, Faculty of Health and Life Sciences, Brownlow Hill, Liverpool, L69 3GB, United Kingdom. Electronic address: sumakafe@liverpool.ac.uk.
  2. Andreas Otto Reiff: Arthritis & Rheumatic Diseases, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, OR 97239, United States. Electronic address: reiffa@ohsu.edu.
PMID: 34563684 DOI: 10.1016/j.clim.2021.108849

Abstract

Numerous reviews have summarized the epidemiology, pathophysiology and the various therapeutic aspects of Coronavirus disease 2019 (COVID-19), but a practical guide on "how to treat whom with what and when" based on an understanding of the immunological background of the disease stages remains missing. This review attempts to combine the current knowledge about the immunopathology of COVID-19 with published evidence of available and emerging treatment options. We recognize that the information about COVID-19 and its treatment is rapidly changing, but hope that this guide offers those on the frontline of this pandemic an understanding of the host response in COVID-19 patients and supports their ongoing efforts to select the best treatments tailored to their patient's clinical status.

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MeSH Term

Animals
COVID-19
Humans
SARS-CoV-2
COVID-19 Drug Treatment
Journal Article Review
Article has an altmetric score of 7

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