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Current neuropharmacology
Mar 04, 2022;20 (3): 648-660.

Melatonin: a Potential Shield against Electromagnetic Waves.

Maya Jammoul, Nada Lawand
Author Information
  1. Maya Jammoul: Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
  2. Nada Lawand: Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
PMID: 34635042 DOI: 10.2174/1570159X19666210609163946

Abstract

Melatonin, a vital hormone synthesized by the pineal gland, has been implicated in various physiological functions and circadian rhythm regulation. Its role in the protection against the non-ionizing electromagnetic field (EMF), known to disrupt the body's oxidative/anti-oxidative balance, has been called into question due to inconsistent results observed across studies. This review provides the current knowledge on the interwoven relationship between melatonin, EMF, and oxidative stress. Based on synthesized evidence, we present a model that best describes the mechanisms underlying the protective effects of melatonin against RF/ELF-EMF-induced oxidative stress. It has been observed that the free radical scavenger activity of melatonin can be enabled by reducing the radical pair singlet-triplet conversion rate and the concentration of the triplet products. Moreover, this review aims to highlight the potential therapeutic benefits of melatonin against the detrimental effects of EMF, in general, and electromagnetic hypersensitivity (EHS), in particular.

Keywords

Antioxidant system electrohypersensitivity electromagnetic field melatonin oxidative stress radical pair mechanism

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MeSH Term

Circadian Rhythm
Electromagnetic Fields
Electromagnetic Radiation
Humans
Melatonin
Oxidative Stress
Pineal Gland

Chemicals

Melatonin
Journal Article Review
Article has an altmetric score of 16

Word Cloud

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