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Aging clinical and experimental research
Apr, 2022;34 (4): 913-925.

Is endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) reliable and safe procedure in geriatric patients?

Aslıhan Gürün Kaya, Aydın Çiledağ, Serhat Erol, Miraç Öz, Deniz Doğan Mülazımoğlu, Özlem Işık, Fatma Çiftçi, Elif Şen, Koray Ceyhan, Demet Karnak, Gökhan Çelik, Akın Kaya, İsmail Savaş
Author Information
  1. Aslıhan Gürün Kaya: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey. agkaya@ankara.edu.tr. ORCID
  2. Aydın Çiledağ: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  3. Serhat Erol: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  4. Miraç Öz: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  5. Deniz Doğan Mülazımoğlu: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  6. Özlem Işık: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  7. Fatma Çiftçi: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  8. Elif Şen: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  9. Koray Ceyhan: Department of Pathology, Faculty of Medicine, Ankara University, Ankara, Turkey.
  10. Demet Karnak: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  11. Gökhan Çelik: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  12. Akın Kaya: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
  13. İsmail Savaş: Department of Chest Diseases, Faculty of Medicine, Ankara University, 06620, Ankara, Turkey.
PMID: 34731449 DOI: 10.1007/s40520-021-02012-9

Abstract

BACKGROUND: Even though studies have indicated the usefulness and safety of endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA), elderly patient data are limited due to the small sample sizes.
AIM: We aimed to evaluate usage and safety of EBUS-TBNA in elderly population.
METHODS: This single-center retrospective study was conducted with patients who underwent an EBUS-TBNA procedure between September 2011 and December 2019. The patients were categorized into two groups: those aged 65 years or older (elderly group) and those younger than 65 years (younger group).
RESULTS: 2444 patient data, 1069 of which were in the elderly group, were analyzed. The cytological examination of EBUS-TBNA identified specimen adequacy in 96.8% of patients. One hundred and thirty patients (5.3%) experienced complications, with similar complication rates recorded in both the elderly and younger groups (5.4% vs 5.2%, p: 0.836). Logistic regression analyses revealed that age, and presence of hypertension, diabetes mellitus, coronary artery disease and malignancy are associated significantly with complication-related EBUS-TBNA. For the lymph nodes with a final diagnosis of malignancy, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of EBUS-TBNA revealed a diagnostic performance in excess of 90% except for metastasis and lymphoma.
CONCLUSION: EBUS-TBNA can be considered a safe and effective technique in patients aged 65 years and over.

Keywords

Complication Elderly Endobronchial ultrasound Geriatric population Safety Transbronchial needle aspiration

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MeSH Term

Aged
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Humans
Lymph Nodes
Predictive Value of Tests
Retrospective Studies
Ultrasonography
Journal Article
Article has an altmetric score of 1

Word Cloud

Created with Highcharts 10.0.0EBUS-TBNAelderlypatientsneedleaspiration65 yearsgroupyounger5safetyendobronchialultrasound-transbronchialpatientdatapopulationprocedureagedrevealedmalignancypredictivevaluesafeBACKGROUND:EventhoughstudiesindicatedusefulnesslimitedduesmallsamplesizesAIM:aimedevaluateusageMETHODS:single-centerretrospectivestudyconductedunderwentSeptember2011December2019categorizedtwogroups:olderRESULTS:24441069analyzedcytologicalexaminationidentifiedspecimenadequacy968%Onehundredthirty3%experiencedcomplicationssimilarcomplicationratesrecordedgroups4%vs2%p:0836Logisticregressionanalysesagepresencehypertensiondiabetesmellituscoronaryarterydiseaseassociatedsignificantlycomplication-relatedlymphnodesfinaldiagnosissensitivityspecificitypositivenegativeaccuracydiagnosticperformanceexcess90%exceptmetastasislymphomaCONCLUSION:canconsideredeffectivetechniqueoverreliablegeriatricpatients?ComplicationElderlyEndobronchialultrasoundGeriatricSafetyTransbronchial

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