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Translational pediatrics
Oct, 2021;10 (10): 2496-2505.

Factors influencing the quality of life in children after biliary atresia treatment.

Yuanyuan Liang, He Yu, Fanke Shu, Wenjiao Huang, Xiaoping Jiang, Zhicheng Xu, Ting Zhang, Bo Xiang, Shuguang Jin
Author Information
  1. Yuanyuan Liang: Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
  2. He Yu: West China School of Clinical Medicine, Sichuan University, Chengdu, China.
  3. Fanke Shu: Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
  4. Wenjiao Huang: Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
  5. Xiaoping Jiang: Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
  6. Zhicheng Xu: Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
  7. Ting Zhang: Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
  8. Bo Xiang: Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
  9. Shuguang Jin: Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
PMID: 34765473 DOI: 10.21037/tp-21-391

Abstract

BACKGROUND: Despite surgical treatment, children with biliary atresia (BA) may face many problems which seriously affect their quality of life. However, there is a paucity of studies in China examining the quality of life of these children after BA treatment. This study investigated the current status of the quality of life of children after BA treatment and analyzed the influencing factors so as to provide a scientific basis for the development of targeted interventional measures.
METHODS: From May 1 to May 31, 2021, the STAR questionnaire method was used to conduct cross-sectional surveys in children following BA surgery in the West China Hospital of Sichuan University, China. The basic information questionnaire was used to investigate the general characteristics of the children. The children were also given quality of life questionnaires during follow-up sessions after surgical treatment for BA. In addition, a 12-point health survey was used to assess the physical and mental health of the children's caregivers. Age- and gender-matched healthy children were recruited as controls. Correlation analysis and multiple linear regression equations were established to explore the influencing factors of the quality of life of children after surgery for BA.
RESULTS: After surgery, children with BA experienced significantly lower physical health, emotional function, social function, cognitive function, and quality of life compared to healthy children (P<0.050). Co-existing diseases had a statistically significant impact on the quality of life of children with BA (b=-12.566; t=-2.343; P=0.021), and the caregiver's understanding level of liver transplantation also had a statistically significant impact on the quality of life of these children (b=6.481; t=2.376; P=0.021).
CONCLUSIONS: The quality of life of children after BA surgery was significantly lower than that of age-matched healthy children. Co-existing diseases and the caregiver's understanding level of liver transplantation were the main factors affecting the quality of life of these children.

Keywords

12-item health survey Biliary atresia (BA) children’s quality of life questionnaire influencing factors quality of life

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Journal Article

Word Cloud

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