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12 03, 2021;11 (1): 23403.

Modulation of magnetoencephalography alpha band activity by radiofrequency electromagnetic field depicted in sensor and source space.

Jasmina Wallace, Lydia Yahia-Cherif, Christophe Gitton, Laurent Hugueville, Jean-Didier Lemaréchal, Brahim Selmaoui
Author Information
  1. Jasmina Wallace: Department of Experimental Toxicology and Modeling (TEAM), Institut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique Alata, BP 2, 60550, Verneuil-en-Halatte, France.
  2. Lydia Yahia-Cherif: Centre De NeuroImagerie De Recherche (CENIR), Institut du Cerveau et de la Moelle épinière (ICM), 75013, Paris, France.
  3. Christophe Gitton: Centre De NeuroImagerie De Recherche (CENIR), Institut du Cerveau et de la Moelle épinière (ICM), 75013, Paris, France.
  4. Laurent Hugueville: Centre De NeuroImagerie De Recherche (CENIR), Institut du Cerveau et de la Moelle épinière (ICM), 75013, Paris, France.
  5. Jean-Didier Lemaréchal: Centre De NeuroImagerie De Recherche (CENIR), Institut du Cerveau et de la Moelle épinière (ICM), 75013, Paris, France.
  6. Brahim Selmaoui: Department of Experimental Toxicology and Modeling (TEAM), Institut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique Alata, BP 2, 60550, Verneuil-en-Halatte, France. brahim.selmaoui@ineris.fr.
PMID: 34862418 DOI: 10.1038/s41598-021-02560-0

Abstract

Several studies reported changes in spontaneous electroencephalogram alpha band activity related to radiofrequency electromagnetic fields, but findings showed both an increase and a decrease of its spectral power or no effect. Here, we studied the alpha band modulation after 900 MHz mobile phone radiofrequency exposure and localized cortical regions involved in these changes, via a magnetoencephalography (MEG) protocol with healthy volunteers in a double-blind, randomized, counterbalanced crossover design. MEG was recorded during eyes open and eyes closed resting-state before and after radiofrequency exposure. Potential confounding factors, known to affect alpha band activity, were assessed as control parameters to limit bias. Entire alpha band, lower and upper alpha sub-bands MEG power spectral densities were estimated in sensor and source space. Biochemistry assays for salivary biomarkers of stress (cortisol, chromogranin-A, alpha amylase), heart rate variability analysis and high-performance liquid chromatography for salivary caffeine concentration were realized. Results in sensor and source space showed a significant modulation of MEG alpha band activity after the radiofrequency exposure, with different involved cortical regions in relation to the eyes condition, probably because of different attention level with open or closed eyes. None of the control parameters reported a statistically significant difference between experimental sessions.

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MeSH Term

Adult
Biomarkers
Caffeine
Cerebral Cortex
Chromatography, High Pressure Liquid
Cross-Over Studies
Double-Blind Method
Electromagnetic Fields
Female
Humans
Magnetoencephalography
Male
Ocular Physiological Phenomena
Rest
Saliva
Young Adult

Chemicals

Biomarkers
Caffeine
Journal Article Research Support, Non-U.S. Gov't
Article has an altmetric score of 2

Word Cloud

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