Glycemic Control and Diabetes Related Complications in Adults with Type 1 Diabetes Mellitus and ADHD.

Michal Vinker-Shuster, Roy Eldor, Ilan Green, Avivit Golan-Cohen, Iris Manor, Eugene Merzon
Author Information
  1. Michal Vinker-Shuster: Assuta Ashdod University Hospital, Israel. ORCID
  2. Roy Eldor: Tel Aviv Sourasky Medical Center, Israel.
  3. Ilan Green: Leumit HMO, Tel Aviv, Israel.
  4. Avivit Golan-Cohen: Leumit HMO, Tel Aviv, Israel.
  5. Iris Manor: The Sackler Faculty of Medicine Tel Aviv University, Israel.
  6. Eugene Merzon: Leumit HMO, Tel Aviv, Israel.

Abstract

OBJECTIVE: To assess the correlation of co-morbid ADHD and diabetes-related complications in patients with type-1-diabetes-mellitus (T1DM).
METHODS: A retrospective cross-sectional study was conducted during 2018 using the Leumit-Health-Services(LHS) database. Diabetes-related complications were assessed in patients with T1DM and ADHD (T1DM-ADHD+) and compared with patients with T1DM alone (T1DM-ADHD-).
RESULTS: Out of 789 adult-patients with T1DM, 75 (9.5%) were T1DM-ADHD+, matched to 225 T1DM-ADHD-. HbAC levels were higher in T1DM-ADHD+ patients (8.1% ± 1.6 vs. 7.4% ± 1.2,  < .01), as well as diabetes-related complications: neuropathy (22.7% vs. 5.8%,  < .01), ulcers (8% vs. 0.9%,  < .05), limb amputation (5.3% vs. 0.9%,  < .05), albuminuria (15.5% vs. 2.8%,  < .01), chronic renal failure (10.6% vs. 2.5%,  = .01), and emergency room admissions rate (26.7% vs. 15.1%,  < .05). In sub-analysis, lower average HbAC levels and diabetic ulcer rates were found among ADHD patients treated with stimulants, all  < .05.
CONCLUSION: Co-morbidity of ADHD and T1DM is associated with poor glycemic control and higher complication rates.

Keywords

MeSH Term

Adult
Attention Deficit Disorder with Hyperactivity
Cross-Sectional Studies
Diabetes Complications
Diabetes Mellitus, Type 1
Glycemic Control
Humans
Retrospective Studies

Word Cloud

Created with Highcharts 10.0.0vs<ADHDpatientsT1DM0105T1DM-ADHD+5%28%diabetes-relatedcomplicationsT1DM-ADHD-HbAClevelshigher7%509%15ratesDiabetes1diabetesOBJECTIVE:assesscorrelationco-morbidtype-1-diabetes-mellitusMETHODS:retrospectivecross-sectionalstudyconducted2018usingLeumit-Health-ServicesLHSdatabaseDiabetes-relatedassessedcomparedaloneRESULTS:789adult-patients759matched22581% ± 1674% ± 1wellcomplications:neuropathy22ulcerslimbamputation3%albuminuriachronicrenalfailure106% = emergencyroomadmissionsrate261%sub-analysisloweraveragediabeticulcerfoundamongtreatedstimulantsCONCLUSION:Co-morbidityassociatedpoorglycemiccontrolcomplicationGlycemicControlRelatedComplicationsAdultsTypeMellitusHbA1Ctype

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