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Chemical research in toxicology
03 21, 2022;35 (3): 337-339.

Gerontology through the Eyes of 21st Century Toxicology.

Lakindu S Pathira Kankanamge
Author Information
  1. Lakindu S Pathira Kankanamge: Chemistry and Chemical Biology Department, Northeastern University, Boston, Massachusetts 02115, United States. ORCID
PMID: 34985863 DOI: 10.1021/acs.chemrestox.1c00336

Abstract

Toxicants can cause cells to experience DNA damage, leading them to cellular senescence. Discovering mechanisms of cellular aging from birth to death will ease the process of understanding aging.

References

  1. Cell. 2013 Jun 6;153(6):1194-217 [PMID: 23746838]
  2. Nat Commun. 2020 Jan 13;11(1):236 [PMID: 31932649]
  3. Int J Environ Res Public Health. 2020 Jan 11;17(2): [PMID: 31940870]
  4. J Biol Chem. 2021 Jan-Jun;296:100355 [PMID: 33539926]

Grants

  1. R13 ES033526/NIEHS NIH HHS

MeSH Term

Cellular Senescence
DNA Damage
Geriatrics
Hazardous Substances

Chemicals

Hazardous Substances
Journal Article

Word Cloud

Created with Highcharts 10.0.0cellularagingToxicantscancausecellsexperienceDNAdamageleadingsenescenceDiscoveringmechanismsbirthdeathwilleaseprocessunderstandingGerontologyEyes21stCenturyToxicology

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