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The Journal of infection
05, 2022;84 (5): 722-746.

Intra-host SARS-CoV-2 single-nucleotide variants emerged during the early stage of COVID-19 pandemic forecast population fixing mutations.

Yi Zhang, Ning Jiang, Weiqiang Qi, Tao Li, Yumeng Zhang, Haocheng Zhang, Jing Wu, Zhaoqin Zhu, Jingwen Ai, Chao Qiu, Wenhong Zhang
Author Information
  1. Yi Zhang: Department of Infectious Diseases, National Clinical Research Center for Aging and Medicine, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China.
  2. Ning Jiang: Department of Infectious Diseases, National Clinical Research Center for Aging and Medicine, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering and Institute of Biostatistics, School of Life Sciences, Fudan University, Shanghai, China.
  3. Weiqiang Qi: Shanghai Public Health Clinical Center, Shanghai, China.
  4. Tao Li: Shanghai Public Health Clinical Center, Shanghai, China.
  5. Yumeng Zhang: Department of Infectious Diseases, National Clinical Research Center for Aging and Medicine, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China.
  6. Haocheng Zhang: Department of Infectious Diseases, National Clinical Research Center for Aging and Medicine, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China.
  7. Jing Wu: Department of Infectious Diseases, National Clinical Research Center for Aging and Medicine, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China.
  8. Zhaoqin Zhu: Shanghai Public Health Clinical Center, Shanghai, China. Electronic address: zhaoqinzhu@163.com.
  9. Jingwen Ai: Department of Infectious Diseases, National Clinical Research Center for Aging and Medicine, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China. Electronic address: jingwenai1990@126.com.
  10. Chao Qiu: Department of Infectious Diseases, National Clinical Research Center for Aging and Medicine, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China; Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: qiuchao@fudan.edu.cn.
  11. Wenhong Zhang: Department of Infectious Diseases, National Clinical Research Center for Aging and Medicine, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China; Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering and Institute of Biostatistics, School of Life Sciences, Fudan University, Shanghai, China; Key Laboratory of Medical Molecular Virology (MOE/MOH), Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: zhangwenhong@fudan.edu.cn.
PMID: 35041922 DOI: 10.1016/j.jinf.2022.01.016

Abstract

No abstract text available.

Keywords

COVID-19 Fixed mutation Intra-host single-nucleotide variants SARS-CoV-2

References

  1. Clin Microbiol Infect. 2020 Nov;26(11):1560.e1-1560.e4 [PMID: 32717416]
  2. Genome Med. 2021 Feb 22;13(1):30 [PMID: 33618765]
  3. Genomics Proteomics Bioinformatics. 2020 Dec;18(6):749-759 [PMID: 33704069]
  4. Science. 2021 Apr 16;372(6539): [PMID: 33688063]
  5. Sci Adv. 2020 Jun 17;6(25):eabb5813 [PMID: 32596474]
  6. J Infect. 2020 Sep;81(3):e48-e50 [PMID: 32593658]
  7. Science. 2021 Feb 19;371(6531):850-854 [PMID: 33495308]
  8. Nat Microbiol. 2016 Sep 05;1(11):16151 [PMID: 27595345]
  9. Nat Rev Microbiol. 2021 Jul;19(7):409-424 [PMID: 34075212]

MeSH Term

COVID-19
Genome, Viral
Humans
Mutation
Nucleotides
Pandemics
SARS-CoV-2
Spike Glycoprotein, Coronavirus

Chemicals

Nucleotides
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2
Letter Research Support, Non-U.S. Gov't

Word Cloud

Created with Highcharts 10.0.0Intra-hostSARS-CoV-2single-nucleotidevariantsCOVID-19emergedearlystagepandemicforecastpopulationfixingmutationsFixedmutation

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