Mohammed H Bogari, Aseel S Jarwan, Abdullah O Abukhodair, Basil A Alzahrani, Jawad A Alsayegh, Alaa Al-Kathiri, Abdulhalim J Kinsara
OBJECTIVES: This study aimed to analyze all the reported cases of definitive Infective Endocarditis, based on the modified Duke criteria in a tertiary hospital over the past five years, focusing on the causative organism/s, predisposing factors, and outcomes.
METHODS: This is a cross-sectional retrospective study. patients with a confirmed diagnosis of Infective Endocarditis using modified Duke criteria were included. The demographic data, predisposing factors, the causative microorganisms, laboratory and echocardiography results, and treatment were collected.
RESULTS: In total, 37 patients were identified, 22 were male, and the median age was 59 years. Native valve endocarditis was found in 29 (78.3%) patients. The most frequently involved valves were the mitral valve in eight (42.1%) and aortic valve in six (31.6%) patients. Fever occurred in 22 patients (59.5%). The most frequent organisms were in 14 (37.4%) patients, coagulase-negative staphylococci in seven (18.9%) patients, and streptococci in seven (18.9%) patients. The majority (n=27) of the patients (72.97%) were treated medically, with 10 (27.02%) requiring in-hospital surgical intervention. The in-hospital mortality rate was 24.3%. Late presentation, reluctance to undergo surgery, and the past history of rheumatic Fever were the contributing factors.
CONCLUSION: Native valve endocarditis is the major type of Infective Endocarditis. The most frequent organisms were , Streptococcus, and coagulase-negative staphylococci. In our study, Infective Endocarditis was more common among males, surgical intervention was low, and a high in-hospital mortality rate was noted in our series.
