Geographic and Ethnic Variations in Serum Concentrations of Legacy Persistent Organic Pollutants among Men in the Nenets Autonomous Okrug, Arctic Russia.
Yulia Varakina, Andrey Aksenov, Dmitry Lakhmanov, Anna Trofimova, Rimma Korobitsyna, Natalia Belova, Dmitry Kotsur, Tatiana Sorokina, Andrej M Grjibovski, Ludmila Popova, Valery Chashchin, Jon Øyvind Odland, Yngvar Thomassen
Author Information
Yulia Varakina: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. ORCID
Andrey Aksenov: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. ORCID
Dmitry Lakhmanov: Laboratory of Environmental Analytical Chemistry, Core Facility Center "Arktika", Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia.
Anna Trofimova: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. ORCID
Rimma Korobitsyna: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. ORCID
Natalia Belova: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia.
Dmitry Kotsur: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia.
Tatiana Sorokina: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. ORCID
Andrej M Grjibovski: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. ORCID
Ludmila Popova: Department of Chemistry and Chemical Ecology, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia.
Valery Chashchin: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. ORCID
Jon Øyvind Odland: Department of Public Health and Nursing, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Yngvar Thomassen: Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. ORCID
The overwhelming majority of Arctic biomonitoring studies in humans include either pregnant or non-pregnant women of reproductive age while little attention is paid to toxic compounds concentrations in men. This study contributes with information of the present amounts of persistent organic pollutants (POPs) in men living in Arctic Russia. We studied the serum concentrations of 11 polychlorinated biphenyl (PCB) congeners and 17 organochlorine pesticides (OCPs) and some of their metabolites in samples collected from 92 adult men (mean age 43 years) from seven different settlements in Nenets Autonomous Okrug (NAO). The median concentrations of individual PCB congeners increased in the order PCB 183, PCB 180, PCB 118, PCB 138, PCB 153. The concentrations of o, p'-DDD, p, p'-DDD, aldrin, mirex and 1,2,3,5-TCB were in most cases below the quantification limit. The observed concentrations of PCBs and chlorinated pesticides were in the same range as those found in similar groups of women of these territories, but lower than of men in other Arctic countries. However, significant geographic differences between the settlements were observed with exceptionally high concentrations of PCBs in the Islands group. The highest serum ∑PCBs and β-HCH levels were observed in adult males aged 60-78 years. We found significant variations in serum concentrations of POPs across settlements and ethnic groups with exceptionally high concentrations of PCBs among the residents of the Arctic islands. At the same time, our findings suggest a considerable decrease in serum concentration of POPs over the last decade.
