Rotation characteristics and neo-commissural alignment of transcatheter heart valve in type-0 bicuspid aortic valve.

Mi Chen, Yan Ding, Honglei Zhao, Junzhou Pu, Bo Yang, Huanyu Qiao, Wei Zhang, Tao Bai, Jinrong Xue, Wenhui Wu, Yongmin Liu, Lizhong Sun, Haibo Zhang
Author Information
  1. Mi Chen: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. ORCID
  2. Yan Ding: Department of Intervention, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  3. Honglei Zhao: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  4. Junzhou Pu: Department of Intervention, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  5. Bo Yang: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  6. Huanyu Qiao: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  7. Wei Zhang: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  8. Tao Bai: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  9. Jinrong Xue: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  10. Wenhui Wu: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  11. Yongmin Liu: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  12. Lizhong Sun: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  13. Haibo Zhang: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. ORCID

Abstract

AIMS: This study sought to characterize the rotation of the transcatheter heart valve (THV) and evaluate the neo-commissures overlap with coronary arteries in type-0 bicuspid aortic valve (BAV).
METHODS AND RESULTS: This was a single-center, 10-patient, retrospective observational cohort. Pre-TAVI computed tomography and procedural fluoroscopy were analyzed. Coplanar fluoroscopic views were coregistered to pre-TAVI computed tomography to characterize THV rotation and determine coronary overlap. The incidence of severe coronary artery overlap with one coronary artery was 90%. According to our prediction line, type-0 BAV has predicted a higher incidence of overlap with one coronary artery, but lower incidence with both coronary arteries compared to the tricuspid aortic valve (TAV). The rotational angles in two different phases were 3.8 ± 3.2° versus 11.8 ± 8.0° (p = .01) in patients with mixed cusp fusion. Commissural angles in final and initial deployment were 9.6 ± 6.6 versus 18.1 ± 11.0° (p = .021). Applying hypothetic "commissure-middle view" in 0°, ±5°, and ±10°, the incidence of overlap with one coronary artery are 20%, 40%, and 90% separately.
CONCLUSIONS: The THV rotation existed and was activated in the last 1/3 deploying phase. With the observed tendency of "automatic commissural alignment," applying the "commissure-middle" view in type-0 BAV may optimize valve alignment and avoid coronary artery overlap.

Keywords

References

  1. Otto CM, Nishimura RA, Bonow RO, Writing Committee M, et al. ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. J Am Coll Cardiol. 2021;77:e25-e197.
  2. Tang GHL, Zaid S, Fuchs A, et al. Alignment of Transcatheter Aortic-Valve Neo-Commissures (ALIGN TAVR): impact on final valve orientation and coronary artery overlap. JACC Cardiovasc Interv. 2020;13(9):1030-1042.
  3. Gunning PS, Vaughan TJ, McNamara LM. Simulation of self expanding transcatheter aortic valve in a realistic aortic root: implications of deployment geometry on leaflet deformation. Ann Biomed Eng. 2014;42(9):1989-2001.
  4. Sievers HH, Schmidtke C. A classification system for the bicuspid aortic valve from 304 surgical specimens. J Thorac Cardiovasc Surg. 2007;133(5):1226-1233.
  5. Jilaihawi H, Chen M, Webb J, et al. A bicuspid aortic valve imaging classification for the TAVR era. JACC Cardiovasc Imaging. 2016;9(10):1145-1158.
  6. Waksman R, Craig PE, Torguson R, et al. Transcatheter aortic valve replacement in low-risk patients with symptomatic severe bicuspid aortic valve stenosis. JACC Cardiovasc Interv. 2020;13(9):1019-1027.
  7. Makkar RR, Yoon SH, Leon MB, et al. Association between transcatheter aortic valve replacement for bicuspid vs tricuspid aortic stenosis and mortality or stroke. JAMA. 2019;321(22):2193-2202.
  8. Yoon SH, Kim WK, Dhoble A, et al. Bicuspid aortic valve morphology and outcomes after transcatheter aortic valve replacement. J Am Coll Cardiol. 2020;76(9):1018-1030.
  9. Komatsu I, Leipsic J, Webb JG, et al. Coronary ostial eccentricity in severe aortic stenosis: guidance for BASILICA transcatheter leaflet laceration. J Cardiovasc Comput Tomogr. 2020;14:516-519.
  10. Tang GHL, Zaid S, Michev I, et al. “Cusp-Overlap” view simplifies fluoroscopy-guided implantation of self-expanding valve in transcatheter aortic valve replacement. JACC Cardiovasc Interv. 2018;11(16):1663-1665.

Grants

  1. /Beijing Municipal Administration of Hospitals
  2. /beijing natural science

MeSH Term

Aortic Valve
Aortic Valve Stenosis
Bicuspid Aortic Valve Disease
Heart Valve Prosthesis
Humans
Prosthesis Design
Retrospective Studies
Rotation
Transcatheter Aortic Valve Replacement
Treatment Outcome

Word Cloud

Created with Highcharts 10.0.0valvecoronaryoverlapaorticarterytranscathetertype-0incidencealignmentheartTHVbicuspidBAVonecharacterizerotationarteriescomputedtomography90%anglesp = commissuralAIMS:studysoughtevaluateneo-commissuresMETHODSANDRESULTS:single-center10-patientretrospectiveobservationalcohortPre-TAVIproceduralfluoroscopyanalyzedCoplanarfluoroscopicviewscoregisteredpre-TAVIdeterminesevereAccordingpredictionlinepredictedhigherlowercomparedtricuspidTAVrotationaltwodifferentphases38 ± 3versus118 ± 801patientsmixedcuspfusionCommissuralfinalinitialdeployment96 ± 66 versus181 ± 11021Applyinghypothetic"commissure-middleview"±5°±10°20%40%separatelyCONCLUSIONS:THV rotationexistedactivatedlast1/3deployingphaseobservedtendency"automatic" applying"commissure-middle"viewmayoptimizeavoidRotationcharacteristicsneo-commissuralimplantation

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