The Complete Chloroplast Genomes of Provide Insight That Neither Species nor Natural Section Represent Monophyletic Taxa in (Primulaceae).

Qiang Li
Author Information
  1. Qiang Li: Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China. ORCID

Abstract

The genus (Primulaceae) comprises more than 500 species, with 300 species distributed in China. The contradictory results between systematic analyses and morphology-based taxonomy make taxonomy studies difficult. Furthermore, frequent introgression between closely related species of can result in non-monophyletic species. In this study, the complete chloroplast genome of sixteen subsp. individuals were assembled and compared with 84 accessions of 74 species from 21 sections of the 24 sections of the genus in China. The plastome sizes of subsp. range from 153,584 bp to 154,028 bp. Genome-wide variations were detected, and 1915 high-quality SNPs and 346 InDels were found. Most SNPs were detected in downstream and upstream gene regions (45.549% and 41.91%). Two cultivated accessions, ZP1 and ZP2, were abundant with SSRs. Moreover, 12 SSRs shared by 9 accessions showed variations that may be used as molecular markers for population genetic studies. The phylogenetic tree showed that subsp. cluster into two independent clades. Two subspecies have highly recognizable morphological characteristics, isolated geographical distribution areas, and distinct phylogenetic relationships compared with subsp. . We elevate the two subspecies of to separate species. Our phylogenetic tree is largely inconsistent with morphology-based taxonomy. Twenty-one sections of were mainly divided into three clades. The monophyly of Sect. , Sect. , Sect. , Sect. , and Sect. are well supported in the phylogenetic tree. The Sect. , Sect. , Sect. , Sect. , Sect. , Sect. , Sect. , and Sect. are not a monophyletic group. The possible explanations for non-monophyly may be hybridization, polyploidization, recent introgression, incorrect taxonomy, or chloroplast capture. Multiple genomic data and population genetic studies are therefore needed to reveal the evolutionary history of . Our results provided valuable information for intraspecific variation and phylogenetic relationships within .

Keywords

References

  1. Mol Phylogenet Evol. 2012 Oct;65(1):23-34 [PMID: 22643289]
  2. Bioinformatics. 2017 Aug 15;33(16):2583-2585 [PMID: 28398459]
  3. Nat Genet. 2011 May;43(5):491-8 [PMID: 21478889]
  4. Sci Rep. 2020 Jul 27;10(1):12473 [PMID: 32719421]
  5. Syst Biol. 2007 Apr;56(2):163-81 [PMID: 17454973]
  6. Trends Ecol Evol. 2009 Jul;24(7):386-93 [PMID: 19409650]
  7. Proc Biol Sci. 2014 Apr 23;281(1784):20140075 [PMID: 24759859]
  8. Bioinformatics. 2015 Oct 15;31(20):3350-2 [PMID: 26099265]
  9. Bioinformatics. 2009 Jul 15;25(14):1754-60 [PMID: 19451168]
  10. Sci Rep. 2020 Nov 27;10(1):20782 [PMID: 33247172]
  11. Front Plant Sci. 2021 Jul 15;12:681270 [PMID: 34335651]
  12. Mol Ecol. 2016 May;25(10):2144-64 [PMID: 26946320]
  13. Plant Divers. 2016 May 24;38(2):59-64 [PMID: 30159450]
  14. Int J Mol Sci. 2018 Apr 01;19(4): [PMID: 29614787]
  15. Genome Biol. 2020 Sep 10;21(1):241 [PMID: 32912315]
  16. Sci Rep. 2021 Mar 4;11(1):5153 [PMID: 33664414]
  17. Mol Phylogenet Evol. 2015 Apr;85:10-21 [PMID: 25585153]
  18. Mitochondrial DNA B Resour. 2019 Jul 24;4(2):2692-2693 [PMID: 33365686]
  19. New Phytol. 2019 Nov;224(3):1290-1303 [PMID: 31077611]
  20. New Phytol. 2006;171(3):617-32 [PMID: 16866963]
  21. Am J Contact Dermat. 1998 Dec;9(4):231-3 [PMID: 9810024]
  22. Nat Prod Lett. 2002 Aug;16(4):249-53 [PMID: 12168760]
  23. Mol Ecol Resour. 2020 Jan;20(1):348-355 [PMID: 31599058]
  24. Biochem Genet. 2008 Feb;46(1-2):75-87 [PMID: 18157690]
  25. Am J Bot. 2004 Jun;91(6):926-42 [PMID: 21653449]
  26. PLoS One. 2017 Sep 1;12(9):e0184257 [PMID: 28863163]
  27. Chin J Nat Med. 2020 Aug;18(8):573-581 [PMID: 32768164]
  28. Nucleic Acids Res. 2019 Jul 2;47(W1):W65-W73 [PMID: 31066451]
  29. PLoS One. 2012;7(9):e41315 [PMID: 23028425]
  30. Int J Genomics. 2020 Sep 5;2020:3236461 [PMID: 32964010]
  31. Mitochondrial DNA B Resour. 2019 Oct 9;4(2):3404-3406 [PMID: 33366014]
  32. Nucleic Acids Res. 2019 Jul 2;47(W1):W59-W64 [PMID: 30949694]
  33. BMC Genomics. 2021 Feb 4;22(1):103 [PMID: 33541261]
  34. PLoS Genet. 2012;8(11):e1002967 [PMID: 23166502]
  35. PLoS One. 2015 Apr 13;10(4):e0122903 [PMID: 25875620]
  36. Fly (Austin). 2012 Apr-Jun;6(2):80-92 [PMID: 22728672]
  37. Ann Bot. 2017 Nov 10;120(5):775-789 [PMID: 28961784]
  38. Mol Biol Evol. 2020 May 1;37(5):1530-1534 [PMID: 32011700]
  39. Physiol Mol Biol Plants. 2020 Oct;26(10):2075-2083 [PMID: 33088051]
  40. Sci Rep. 2021 Jul 28;11(1):15363 [PMID: 34321524]
  41. Mol Phylogenet Evol. 2010 Feb;54(2):647-50 [PMID: 19716428]
  42. BMC Evol Biol. 2014 Jul 07;14:151 [PMID: 25001059]
  43. Bioinformatics. 2012 Jan 15;28(2):298-9 [PMID: 22110245]
  44. BMC Evol Biol. 2012 Apr 24;12:56 [PMID: 22530870]
  45. Mol Phylogenet Evol. 2010 Jan;54(1):235-42 [PMID: 19683588]
  46. Am J Hum Genet. 2007 Sep;81(3):559-75 [PMID: 17701901]
  47. Plant Mol Biol. 2020 Apr;102(6):659-676 [PMID: 31997112]
  48. Sci Rep. 2015 Feb 12;5:8348 [PMID: 25672218]
  49. PeerJ. 2020 Jun 19;8:e9314 [PMID: 32596045]
  50. Nat Rev Genet. 2004 Jun;5(6):435-45 [PMID: 15153996]
  51. Bioinformatics. 2009 Aug 15;25(16):2078-9 [PMID: 19505943]
  52. Front Plant Sci. 2020 Nov 12;11:577536 [PMID: 33281844]
  53. BMC Evol Biol. 2015 Aug 16;15:161 [PMID: 26275399]
  54. Mol Ecol. 2021 Feb;30(3):791-809 [PMID: 33259111]
  55. New Phytol. 2006;171(3):605-16 [PMID: 16866962]
  56. Genome Biol Evol. 2015 Apr 13;7(5):1227-34 [PMID: 25869380]

MeSH Term

Biological Evolution
Genome, Chloroplast
Humans
Phylogeny
Primula
Primulaceae

Word Cloud

Created with Highcharts 10.0.0SectspeciesphylogenetictaxonomysubspstudieschloroplastaccessionssectionstreegenusPrimulaceaeChinaresultsmorphology-basedintrogressiongenomecomparedbpvariationsdetectedSNPsTwoSSRsshowedmaypopulationgenetictwocladessubspeciesrelationshipsintraspecificvariationPrimulacomprises500300distributedcontradictorysystematicanalysesmakedifficultFurthermorefrequentcloselyrelatedcanresultnon-monophyleticstudycompletesixteenindividualsassembled84742124plastomesizesrange153584154028Genome-wide1915high-quality346InDelsfounddownstreamupstreamgeneregions45549%4191%cultivatedZP1ZP2abundantMoreover12shared9usedmolecularmarkersclusterindependenthighlyrecognizablemorphologicalcharacteristicsisolatedgeographicaldistributionareasdistinctelevateseparatelargelyinconsistentTwenty-onemainlydividedthreemonophylywellsupportedmonophyleticgrouppossibleexplanationsnon-monophylyhybridizationpolyploidizationrecentincorrectcaptureMultiplegenomicdatathereforeneededrevealevolutionaryhistoryprovidedvaluableinformationwithinCompleteChloroplastGenomesProvideInsightNeitherSpeciesNaturalSectionRepresentMonophyleticTaxaobconica

Similar Articles

Cited By