Photonics enabled intelligence system to identify SARS-CoV 2 mutations.

Bakr Ahmed Taha, Qussay Al-Jubouri, Yousif Al Mashhadany, Mohd Saiful Dzulkefly Bin Zan, Ahmad Ashrif A Bakar, Mahmoud Muhanad Fadhel, Norhana Arsad
Author Information
  1. Bakr Ahmed Taha: UKM-Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Malaysia.
  2. Qussay Al-Jubouri: Department of Communication Engineering, University of Technology, Baghdad, 00964, Iraq.
  3. Yousif Al Mashhadany: Department of Electrical Engineering, College of Engineering, University of Anbar, Anbar, 00964, Iraq.
  4. Mohd Saiful Dzulkefly Bin Zan: UKM-Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Malaysia.
  5. Ahmad Ashrif A Bakar: UKM-Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Malaysia.
  6. Mahmoud Muhanad Fadhel: UKM-Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Malaysia.
  7. Norhana Arsad: UKM-Department of Electrical, Electronic and Systems Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Malaysia. noa@ukm.edu.my. ORCID

Abstract

The COVID-19, MERS-CoV, and SARS-CoV are hazardous epidemics that have resulted in many deaths which caused a worldwide debate. Despite control efforts, SARS-CoV-2 continues to spread, and the fast spread of this highly infectious illness has posed a grave threat to global health. The effect of the SARS-CoV-2 mutation, on the other hand, has been characterized by worrying variations that modify viral characteristics in response to the changing resistance profile of the human population. The repeated transmission of virus mutation indicates that epidemics are likely to occur. Therefore, an early identification system of ongoing mutations of SARS-CoV-2 will provide essential insights for planning and avoiding future outbreaks. This article discussed the following highlights: First, comparing the omicron mutation with other variants; second, analysis and evaluation of the spread rate of the SARS-CoV 2 variations in the countries; third, identification of mutation areas in spike protein; and fourth, it discussed the photonics approaches enabled with artificial intelligence. Therefore, our goal is to identify the SARS-CoV 2 virus directly without the need for sample preparation or molecular amplification procedures. Furthermore, by connecting through the optical network, the COVID-19 test becomes a component of the Internet of healthcare things to improve precision, service efficiency, and flexibility and provide greater availability for the evaluation of the general population. KEY POINTS: • A proposed framework of photonics based on AI for identifying and sorting SARS-CoV 2 mutations. • Comparative scatter rates Omicron variant and other SARS-CoV 2 variations per country. • Evaluating mutation areas in spike protein and AI enabled by photonic technologies for SARS-CoV 2 virus detection.

Keywords

References

  1. Cell. 2021 Jan 7;184(1):64-75.e11 [PMID: 33275900]
  2. J Med Virol. 2020 Sep;92(9):1410-1412 [PMID: 32275082]
  3. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23652-23662 [PMID: 32868447]
  4. Sci Rep. 2017 Jul 18;7(1):5742 [PMID: 28720758]
  5. Cell. 2021 Apr 29;184(9):2348-2361.e6 [PMID: 33730597]
  6. Anal Chem. 2020 Feb 4;92(3):2731-2738 [PMID: 31944675]
  7. Per Med. 2018 Sep;15(5):429-448 [PMID: 30259801]
  8. Light Sci Appl. 2018 Apr 20;7:18003 [PMID: 30839538]
  9. Nature. 2021 Dec;600(7887):21 [PMID: 34824381]
  10. N Engl J Med. 2021 Feb 11;384(6):497-511 [PMID: 33264556]
  11. Nature. 2021 Apr;592(7852):116-121 [PMID: 33106671]
  12. Pathogens. 2020 Jul 13;9(7): [PMID: 32668692]
  13. Heliyon. 2021 Sep;7(9):e07936 [PMID: 34514180]
  14. Diabetes Metab Syndr. 2020 Sep - Oct;14(5):797-799 [PMID: 32534432]
  15. ACS Omega. 2021 Oct 29;6(44):29268-29290 [PMID: 34778604]
  16. Genomics Proteomics Bioinformatics. 2020 Dec;18(6):648-663 [PMID: 33581339]
  17. Biosens Bioelectron. 2019 Apr 15;131:60-66 [PMID: 30826651]
  18. IEEE Trans Med Imaging. 2001 Aug;20(8):730-41 [PMID: 11513024]
  19. PLoS One. 2021 Apr 14;16(4):e0249394 [PMID: 33852588]
  20. Micromachines (Basel). 2020 Jan 21;11(2): [PMID: 31973061]
  21. Cell. 2021 Apr 29;184(9):2384-2393.e12 [PMID: 33794143]
  22. ACS Nano. 2014 Jul 22;8(7):7340-9 [PMID: 24979060]
  23. ACS Nano. 2013 Oct 22;7(10):9147-55 [PMID: 24016065]
  24. Heliyon. 2021 Mar;7(3):e06572 [PMID: 33778179]
  25. Ultramicroscopy. 2005 Sep;104(2):152-9 [PMID: 15890445]
  26. Opt Lett. 1994 Jun 1;19(11):780-2 [PMID: 19844443]
  27. Adv Mater. 2020 Sep;32(37):e2001994 [PMID: 32715536]
  28. J Infect. 2021 Apr;82(4):e27-e28 [PMID: 33383088]
  29. J Med Virol. 2022 Apr;94(4):1255-1256 [PMID: 34850421]
  30. J Cell Immunol. 2021;3(2):103-108 [PMID: 33969357]
  31. Cell. 2020 Aug 20;182(4):812-827.e19 [PMID: 32697968]
  32. Gene Rep. 2021 Jun;23:101064 [PMID: 33681535]
  33. Emerg Infect Dis. 2022 Feb;28(2):460-462 [PMID: 34860154]
  34. Eur J Phys Rehabil Med. 2020 Jun;56(3):327-330 [PMID: 32329593]
  35. Intensive Care Med. 2020 Apr;46(4):586-590 [PMID: 32125455]
  36. Nat Commun. 2018 Feb 26;9(1):815 [PMID: 29483548]
  37. J Infect. 2020 Jun;80(6):656-665 [PMID: 32283155]
  38. Sensors (Basel). 2020 Nov 26;20(23): [PMID: 33256085]
  39. Aesthetic Plast Surg. 2021 Apr;45(2):777-783 [PMID: 32869133]
  40. Sci Rep. 2017 Aug 7;7(1):7430 [PMID: 28784997]
  41. Virology. 1995 Nov 10;213(2):569-80 [PMID: 7491781]
  42. Science. 2021 Apr 9;372(6538): [PMID: 33658326]
  43. J Hosp Infect. 2020 Mar;104(3):246-251 [PMID: 32035997]
  44. Sci Rep. 2016 Dec 19;6:39317 [PMID: 27991574]
  45. Viruses. 2020 Mar 25;12(4): [PMID: 32218151]
  46. J Autoimmun. 2021 Nov;124:102715 [PMID: 34399188]
  47. J Am Coll Cardiol. 2003 Aug 6;42(3):576-82 [PMID: 12906991]
  48. Nanoscale. 2013 Aug 7;5(15):6720-4 [PMID: 23783734]
  49. Chem Commun (Camb). 2020 Sep 11;56(70):10235-10238 [PMID: 32756614]
  50. Biosens Bioelectron. 2021 Jun 1;181:113160 [PMID: 33740542]
  51. Biosensors (Basel). 2021 Jul 27;11(8): [PMID: 34436055]
  52. N Engl J Med. 2020 Mar 19;382(12):1177-1179 [PMID: 32074444]
  53. Nat Commun. 2020 May 27;11(1):2688 [PMID: 32461612]
  54. Trends Genet. 2021 Apr;37(4):299-302 [PMID: 33402270]
  55. Biosens Bioelectron. 2021 Apr 15;178:113004 [PMID: 33497877]
  56. Anal Chem. 2014 Sep 2;86(17):8805-13 [PMID: 25098859]
  57. Sci Rep. 2015 Jun 04;5:10925 [PMID: 26043396]
  58. Biosens Bioelectron. 2018 Jan 15;99:513-518 [PMID: 28823976]
  59. Sci Adv. 2018 Jan 05;4(1):eaao0773 [PMID: 29326979]
  60. Nature. 1990 Jan 25;343(6256):325-30 [PMID: 2300184]
  61. J Biol Chem. 2021 Oct;297(4):101238 [PMID: 34563540]
  62. Biomedicines. 2021 Sep 23;9(10): [PMID: 34680420]
  63. Nature. 2020 Oct;586(7830):516-527 [PMID: 32967006]
  64. J Biomol Struct Dyn. 2021 Jun;39(9):3409-3418 [PMID: 32306836]
  65. Cell Host Microbe. 2021 Jan 13;29(1):23-31.e4 [PMID: 33306985]
  66. Gene Ther. 2012 Mar;19(3):279-87 [PMID: 21753796]
  67. Microorganisms. 2021 Mar 15;9(3): [PMID: 33804162]
  68. J Biomol Struct Dyn. 2021 May;39(8):3025-3033 [PMID: 32274964]
  69. Opt Lett. 1993 Nov 1;18(21):1867-9 [PMID: 19829431]
  70. Opt Express. 2009 Dec 7;17(25):22767-72 [PMID: 20052202]
  71. Am J Otolaryngol. 2021 May-Jun;42(3):102928 [PMID: 33545447]
  72. J Med Internet Res. 2020 Jul 2;22(7):e19514 [PMID: 32568727]
  73. ACS Nano. 2021 Sep 28;15(9):15362-15370 [PMID: 34463475]
  74. Mater Today Proc. 2021 Aug 4;: [PMID: 34373829]
  75. JAMA. 2020 Jun 9;323(22):2249-2251 [PMID: 32374370]
  76. PLoS Biol. 2017 Jan 12;15(1):e2001402 [PMID: 28081144]
  77. Emerg Med J. 2020 Jun;37(6):335-337 [PMID: 32366616]
  78. Transbound Emerg Dis. 2021 Mar;68(2):296-312 [PMID: 32603505]
  79. Lancet Microbe. 2021 Jun;2(6):e238 [PMID: 34100006]
  80. Science. 2006 Sep 15;313(5793):1642-5 [PMID: 16902090]
  81. Cell. 2020 Aug 20;182(4):794-795 [PMID: 32697970]
  82. Light Sci Appl. 2019 May 8;8:42 [PMID: 31098012]
  83. Environ Sci Technol Lett. 2021 Feb 9;8(2):168-175 [PMID: 34192125]
  84. Cell. 2020 Oct 29;183(3):739-751.e8 [PMID: 32991842]
  85. Diagnostics (Basel). 2021 Jun 19;11(6): [PMID: 34205401]
  86. JAMA. 2021 Feb 9;325(6):529-531 [PMID: 33404586]
  87. Cell. 2020 May 14;181(4):894-904.e9 [PMID: 32275855]
  88. Cell Mol Life Sci. 2016 Dec;73(23):4433-4448 [PMID: 27392606]

MeSH Term

Artificial Intelligence
COVID-19
Humans
Intelligence
Mutation
Optics and Photonics
SARS-CoV-2
Spike Glycoprotein, Coronavirus

Chemicals

Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2

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