A Survey of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) practices in India.

Karan Madan, Saurabh Mittal, Pawan Tiwari, Vijay Hadda, Anant Mohan, Randeep Guleria
Author Information
  1. Karan Madan: Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.
  2. Saurabh Mittal: Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.
  3. Pawan Tiwari: Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.
  4. Vijay Hadda: Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.
  5. Anant Mohan: Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.
  6. Randeep Guleria: Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.

Abstract

Background: There is a lack of data on the prevalent practices of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in India.
Aim: To study the current practices of EBUS-TBNA in India.
Methods: This survey was an online questionnaire designed on the Google forms interface. The survey included various questions related to demographics, sedation, analgesia and anesthesia, technical aspects, and infection control related to the procedure of EBUS-TBNA.
Results: Data from 134 respondents (mean age: 42.2 years) were analyzed. Most (97.8%) were pulmonologists or physicians, and a majority (94.8%) practicing in either a private multi-specialty setting or medical college. 40.3% had received procedure training at a formal training program. Mild/moderate sedation was the most common strategy (70.1%). Midazolam (76.7%), Fentanyl (76.0%), followed by propofol (46.5%), were the most frequent drugs, and 82.8% preferred combination sedation. 26.1% used cricothyroid lignocaine injection, and the use of 1% or 2% lignocaine for spray-as-you-go administration was similar. The oral route was preferred, while the laryngeal mask airway was the most common airway conduit under general anesthesia. Suspected granulomatous mediastinal lymphadenopathy (TB/sarcoidosis) (67.2%), followed by lung cancer (32.8%), were the most common indications of EBUS-TBNA. 81.3% performed EBUS-TBNA for lung cancer staging. 21 G needle was preferred (64.9%), and vacuum suction was common (80.6%). 55.2% routinely performed ROSE. Alcohol fixed glass slide smears were the most common method (93.1%) for cytological preparation. 49.3% also performed EUS-B-FNA. 76.9% routinely obtained endo bronchial biopsy and transbronchial lung biopsy in patients with suspected sarcoidosis. Elastography was infrequently used. Nearly three-fourths (77.6%) reused EBUS needles.
Conclusion: There is practice variability in the multiple aspects related technical performance of EBUS-TBNA. Evidence-based guidelines addressing the multiple technical aspects are required to standardize the practice of EBUS-TBNA.

Keywords

References

  1. Indian J Pediatr. 2015 Apr;82(4):378-80 [PMID: 25567076]
  2. Thorax. 1990 Jun;45(6):474-7 [PMID: 2392794]
  3. Respirology. 2011 Jan;16(1):90-4 [PMID: 20920141]
  4. Lung India. 2016 Jul-Aug;33(4):367-71 [PMID: 27578927]
  5. J Bronchology Interv Pulmonol. 2017 Jan;24(1):48-58 [PMID: 27984385]
  6. Lung India. 2018 Nov-Dec;35(6):467-471 [PMID: 30381554]
  7. Respirology. 2022 Feb;27(2):152-160 [PMID: 34792268]
  8. J Bronchology Interv Pulmonol. 2014 Jul;21(3):208-14 [PMID: 24992128]
  9. Chest. 2016 Mar;149(3):816-35 [PMID: 26402427]
  10. Lung India. 2020 Sep-Oct;37(5):384-388 [PMID: 32883896]
  11. Clin Respir J. 2020 Nov;14(11):1076-1082 [PMID: 32748463]
  12. Lung India. 2021 Jan-Feb;38(1):23-30 [PMID: 33402634]
  13. J Bronchology Interv Pulmonol. 2015 Oct;22(4):347-50 [PMID: 26492608]
  14. J Ultrasound Med. 2022 May;41(5):1301-1302 [PMID: 34278589]
  15. Lung India. 2021 May-Jun;38(3):223-228 [PMID: 33942745]
  16. Lung India. 2020 Sep-Oct;37(5):449-450 [PMID: 32883909]
  17. Indian J Anaesth. 2018 Feb;62(2):150-151 [PMID: 29491526]
  18. Pediatr Pulmonol. 2021 Jan;56(1):23-33 [PMID: 33073498]
  19. Lung India. 2015 Jan-Feb;32(1):6-10 [PMID: 25624588]
  20. Adv Respir Med. 2021;89(3):268-276 [PMID: 34196379]
  21. Adv Respir Med. 2021;89(2):229-230 [PMID: 33871039]
  22. JAMA. 2013 Oct 16;310(15):1624 [PMID: 24129468]
  23. Chest. 2016 Apr;149(4):1111-3 [PMID: 27055709]
  24. Thorax. 2003 Dec;58(12):1083-6 [PMID: 14645981]
  25. Respirology. 2011 Jan;16(1):102-6 [PMID: 20920136]
  26. J Bronchology Interv Pulmonol. 2018 Apr;25(2):103-110 [PMID: 29346249]
  27. Endosc Ultrasound. 2016 Sep-Oct;5(5):300-306 [PMID: 27803902]
  28. Respir Care. 2019 Mar;64(3):358-359 [PMID: 30850555]
  29. Expert Rev Respir Med. 2021 Oct;15(10):1317-1334 [PMID: 33888038]
  30. Expert Rev Med Devices. 2021 Feb;18(2):211-216 [PMID: 33435733]
  31. Pediatr Pulmonol. 2019 Jun;54(6):881-885 [PMID: 30891940]
  32. Chest. 2018 Apr;153(4):929-938 [PMID: 29154972]
  33. J Bronchology Interv Pulmonol. 2017 Jan;24(1):7-14 [PMID: 27984382]
  34. Chest. 2020 Jan;157(1):198-204 [PMID: 31299247]
  35. Lung India. 2021 Sep-Oct;38(5):416-424 [PMID: 34472518]
  36. Respiration. 2019;98(5):440-446 [PMID: 31461720]
  37. Lung India. 2018 Mar-Apr;35(2):98-107 [PMID: 29487243]
  38. Pediatr Pulmonol. 2016 Oct;51(10):1031-1039 [PMID: 27142997]
  39. Chest. 2014 Sep;146(3):547-556 [PMID: 24481031]
  40. Lung India. 2019 Jul-Aug;36(4):288-294 [PMID: 31290412]
  41. J Bronchology Interv Pulmonol. 2018 Oct;25(4):264-268 [PMID: 29771776]

Word Cloud

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