An early warning system for emerging SARS-CoV-2 variants.
Lorenzo Subissi, Anne von Gottberg, Lipi Thukral, Nathalie Worp, Bas B Oude Munnink, Surabhi Rathore, Laith J Abu-Raddad, Ximena Aguilera, Erik Alm, Brett N Archer, Homa Attar Cohen, Amal Barakat, Wendy S Barclay, Jinal N Bhiman, Leon Caly, Meera Chand, Mark Chen, Ann Cullinane, Tulio de Oliveira, Christian Drosten, Julian Druce, Paul Effler, Ihab El Masry, Adama Faye, Simani Gaseitsiwe, Elodie Ghedin, Rebecca Grant, Bart L Haagmans, Belinda L Herring, Shilpa S Iyer, Zyleen Kassamali, Manish Kakkar, Rebecca J Kondor, Juliana A Leite, Yee-Sin Leo, Gabriel M Leung, Marco Marklewitz, Sikhulile Moyo, Jairo Mendez-Rico, Nada M Melhem, Vincent Munster, Karen Nahapetyan, Djin-Ye Oh, Boris I Pavlin, Thomas P Peacock, Malik Peiris, Zhibin Peng, Leo L M Poon, Andrew Rambaut, Jilian Sacks, Yinzhong Shen, Marilda M Siqueira, Sofonias K Tessema, Erik M Volz, Volker Thiel, Sylvie van der Werf, Sylvie Briand, Mark D Perkins, Maria D Van Kerkhove, Marion P G Koopmans, Anurag Agrawal
Author Information
- Lorenzo Subissi: World Health Organization, Geneva, Switzerland. ORCID
- Anne von Gottberg: National Institute for Communicable Diseases, Johannesburg, South Africa. ORCID
- Lipi Thukral: CSIR Institute of Genomics and Integrative Biology, Delhi, India.
- Nathalie Worp: Erasmus Medical Centre, Rotterdam, the Netherlands.
- Bas B Oude Munnink: Erasmus Medical Centre, Rotterdam, the Netherlands. ORCID
- Surabhi Rathore: CSIR Institute of Genomics and Integrative Biology, Delhi, India.
- Laith J Abu-Raddad: Weill Cornell Medicine - Qatar of Cornell University, Doha, Qatar. ORCID
- Ximena Aguilera: Epidemiology and Health Policy Centre, Universidad del Desarollo, Santiago, Chile. ORCID
- Erik Alm: European Centre for Disease Prevention and Control, Stockholm, Sweden.
- Brett N Archer: World Health Organization, Geneva, Switzerland. ORCID
- Homa Attar Cohen: World Health Organization, Geneva, Switzerland.
- Amal Barakat: World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.
- Wendy S Barclay: Imperial College London, London, UK. ORCID
- Jinal N Bhiman: National Institute for Communicable Diseases, Johannesburg, South Africa. ORCID
- Leon Caly: Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia.
- Meera Chand: UK Health Security Agency, London, UK.
- Mark Chen: National Centre for Infectious Diseases, Singapore, Singapore.
- Ann Cullinane: World Organisation for Animal Health, Paris, France.
- Tulio de Oliveira: Centre for Epidemic Response and Innovation, Stellenbosch University, Stellenbosch, South Africa.
- Christian Drosten: Charit�� Medical Center, Berlin, Germany. ORCID
- Julian Druce: Epidemiology and Health Policy Centre, Universidad del Desarollo, Santiago, Chile.
- Paul Effler: University of Western Australia, Perth, Western Australia, Australia.
- Ihab El Masry: Food and Agriculture Organization, Rome, Italy.
- Adama Faye: Institut de Sant�� et D��veloppement, Universit�� Cheikh Anta Diop, Dakar, Senegal.
- Simani Gaseitsiwe: Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
- Elodie Ghedin: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. ORCID
- Rebecca Grant: World Health Organization, Geneva, Switzerland.
- Bart L Haagmans: Erasmus Medical Centre, Rotterdam, the Netherlands. ORCID
- Belinda L Herring: World Health Organization Regional Office for Africa, Brazzaville, Republic of Congo.
- Shilpa S Iyer: World Health Organization Regional Office for Western Pacific, Manila, The Philippines.
- Zyleen Kassamali: World Health Organization, Geneva, Switzerland. ORCID
- Manish Kakkar: World Health Organization Regional Office for South-East Asia, New Delhi, India. ORCID
- Rebecca J Kondor: United States Centers for Disease Control and Prevention, Atlanta, GA, USA.
- Juliana A Leite: World Health Organization Regional Office for the Americas, Washington, DC, USA. ORCID
- Yee-Sin Leo: National Centre for Infectious Diseases, Singapore, Singapore. ORCID
- Gabriel M Leung: School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, The People's Republic of China.
- Marco Marklewitz: World Health Organization Regional Office for Europe, Copenhagen, Denmark. ORCID
- Sikhulile Moyo: Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana. ORCID
- Jairo Mendez-Rico: World Health Organization Regional Office for the Americas, Washington, DC, USA.
- Nada M Melhem: American University of Beirut, Beirut, Lebanon. ORCID
- Vincent Munster: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA. ORCID
- Karen Nahapetyan: World Health Organization Regional Office for Europe, Copenhagen, Denmark.
- Djin-Ye Oh: Robert Koch Institute, Berlin, Germany.
- Boris I Pavlin: World Health Organization, Geneva, Switzerland.
- Thomas P Peacock: Imperial College London, London, UK. ORCID
- Malik Peiris: School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, The People's Republic of China. ORCID
- Zhibin Peng: Chinese Center for Disease Control and Prevention, Beijing, The People's Republic of China.
- Leo L M Poon: School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, The People's Republic of China. ORCID
- Andrew Rambaut: University of Edinburgh, Edinburgh, UK. ORCID
- Jilian Sacks: World Health Organization, Geneva, Switzerland.
- Yinzhong Shen: Shanghai Public Health Clinical Center, Fudan University, Shanghai, The People's Republic of China.
- Marilda M Siqueira: Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
- Sofonias K Tessema: Africa Centers for Disease Control and Prevention, Addis Ababa, Ethiopia.
- Erik M Volz: Imperial College London, London, UK. ORCID
- Volker Thiel: Multidisciplinary Center for Infectious Diseases, University of Bern, Bern, Switzerland. ORCID
- Sylvie van der Werf: Institut Pasteur, Universit�� Paris Cit��, Paris, France. ORCID
- Sylvie Briand: World Health Organization, Geneva, Switzerland.
- Mark D Perkins: World Health Organization, Geneva, Switzerland.
- Maria D Van Kerkhove: World Health Organization, Geneva, Switzerland. vankerkhovem@who.int. ORCID
- Marion P G Koopmans: Erasmus Medical Centre, Rotterdam, the Netherlands. ORCID
- Anurag Agrawal: Trivedi School of Biosciences, Ashoka University, Sonipat, India.
No abstract text available.
- World Health Organization. https://www.who.int/publications/m/item/terms-of-reference-for-the-technical-advisory-group-on-sars-cov-2-virus-evolution-(tag-ve) (18 October 2021).
- World Health Organization. https://www.who.int/en/activities/tracking-SARS-CoV-2-variants/ (accessed 15 May 2022).
- World Health Organization. https://apps.who.int/iris/bitstream/handle/10665/163636/WHO_HSE_FOS_15.1_eng.pdf (May 2015).
- Konings, F. et al. New Microbiol. 6, 821���823 (2021).
- World Health Organization. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports (accessed 15 May 2022).
- Syed, A. M. et al. Science 374, 1626���1632 (2021).
[PMID: 34735219]
- Bergeri, I. et al. Preprint at MedRxiv https://doi.org/10.1101/2021.12.14.21267791 (2020).
- World Health Organization. https://www.who.int/initiatives/who-biohub (accessed 15 May 2022).
- Davies, N. G. et al. Nature 593, 270���274 (2021).
[PMID: 33723411]
- Twohig, K. A. et al. Lancet Infect. Dis. 22, 35���42 (2022).
[PMID: 34461056]
- Munster, V. J. et al. Sci. Adv. 7, eabj3627 (2021).
[PMID: 34678071]
- Mu��oz-Fontela, C. et al. PLoS Pathog. 18, e1010161 (2022).
[PMID: 35025969]
- Oude Munnink, B. B. et al. Nat. Med. 27, 1518���1524 (2021).
[PMID: 34504335]
- Viana, R. et al. Nature 603, 679���686 (2022).
[PMID: 35042229]
- Gao, Y. et al. Nat. Med. 28, 472���476 (2022).
[PMID: 35042228]
- Keeton, R. et al. Nature 603, 488���492 (2022).
[PMID: 35102311]
- Kitchin, D. et al. Cell Rep. Med. 3, 100535 (2022).
[PMID: 35474744]
- He, W. et al. Preprint at BioRxiv https://doi.org/10.1101/2021.09.08.459480 (2021).
- Maher, M. C. et al. Sci. Transl. Med. 14, eabk3445 (2022).
[PMID: 35014856]
- Jones, S. et al. Sci. Rep. 9, 14690 (2019).
[PMID: 31604969]
- Corey, L. et al. N. Engl. J. Med. 385, 562���566 (2021).
[PMID: 34347959]
- Oude Munnink, B. B. et al. Science 371, 172���177 (2021).
[PMID: 33172935]
- Grabowski, F., Preibisch, G., Gizi��ski, S., Kocha��czyk, M. & Lipniacki, T. Viruses 13, 392 (2021).
[PMID: 33804556]
- McCallum, M. et al. Cell 184, 2332���2347.e16 (2021).
[PMID: 33761326]
- Wang, P. et al. Nature 593, 130���135 (2021).
[PMID: 33684923]
- Riou, C. et al. Sci. Transl. Med. 14, eabj6824 (2022).
[PMID: 34931886]
- Meng, B. et al. Cell Rep. 35, 109292 (2021).
[PMID: 34166617]
- Liu, Y. et al. Nature 602, 294���299 (2022).
[PMID: 34818667]
- Carre��o, J. M. et al. EBioMed. 73, 103626 (2021).
[DOI: 10.1016/j.ebiom.2021.103626]
- West, A. P. et al. Nat. Commun. 12, 4886 (2021).
[PMID: 34373458]
- McCarthy, K. R. et al. Science 371, 1139���1142 (2021).
[PMID: 33536258]
- Haslwanter, D. et al. mBio 12, 02473���21 (2021).
[DOI: 10.1128/mBio.02473-21]
- Wibmer, C. K. et al. Nat. Med. 27, 622���625 (2021).
[PMID: 33654292]
- Cao, Y. et al. Nature 602, 657���663 (2022).
[PMID: 35016194]
- Starr, T.N. et al. Preprint at BioRxiv https://doi.org/10.1101/2022.02.24.481899 (2022).
- Iketani, S. et al. Nature 604, 553���556 (2022).
[PMID: 35240676]
- Chen, R. E. et al. Nat. Med. 27, 717���726 (2021).
[PMID: 33664494]
- Wang, Z. et al. Nature 592, 616���622 (2021).
[PMID: 33567448]
- Starr, T. N. et al. Science 371, 850���854 (2021).
[PMID: 33495308]
- Weisblum, Y. et al. eLife 9, e61312 (2020).
[PMID: 33112236]
- Garrett Rappazzo, C. et al. Science 371, 823���829 (2021).
[PMID: 33495307]
- Deng, X. et al. Cell 184, 3426���3437 (2021).
[PMID: 33991487]
- Harvey, W. T. et al. Nat. Rev. Microbiol. 19, 409���424 (2021).
[PMID: 34075212]
- Motozono, C. et al. Cell Host Microbe 29, 1124���1136 (2021).
[PMID: 34171266]
- Wang, M. et al. Emerg. Microbes Infect. 11, 18���29 (2022).
[PMID: 34818119]
- Tada, T. et al. Front. Immunol. 13, 797589 (2022).
[PMID: 35350781]
- Starr, T. N. Cell 182, 1295���1310.e20 (2020).
[PMID: 32841599]
- Liu, Z. et al. Cell Host Microbe 29, 477���488 (2021).
[PMID: 33535027]
- Greaney, A. J. et al. Cell Host Microbe 29, 463���476.e6 (2021).
[PMID: 33592168]
- Andreano, E. et al. Proc. Natl Acad. Sci. USA 118, e2103154118 (2021).
[PMID: 34417349]
- Greaney, A. J. et al. Nat. Commun. 12, 4196 (2021).
[PMID: 34234131]
- Li, Q. et al. Cell 184, 2362���2371.e9 (2021).
[PMID: 33735608]
- Collier, D. A. et al. Nature 593, 136���141 (2021).
[PMID: 33706364]
- Volz, E. et al. Cell 184, 64���75.e11 (2021).
[PMID: 33275900]
- Hou, Y. J. et al. Science 370, 1464���1468 (2020).
[PMID: 33184236]
- Escalera, A. et al. Cell Host Microbe 30, 373���387.e7 (2022).
[PMID: 35150638]
- Baum, A. et al. Science 369, 1014���1018 (2020).
[PMID: 32540904]
- Lubinski, B. et al. iScience 25, 103589 (2022).
[PMID: 34909610]
- Liu, Y. et al. Cell Rep. 39, 110829 (2022).
[PMID: 35550680]
- Saito, A. et al. Nature 602, 300���306 (2022).
[PMID: 34823256]
- 001/World Health Organization
- 206298/Z/17/Z/Wellcome Trust
- MR/R015600/1/Medical Research Council
- ZIA AI001324/Intramural NIH HHS
COVID-19
Humans
SARS-CoV-2