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Current HIV/AIDS reports
08, 2022;19 (4): 235-250.

Running with Scissors: a Systematic Review of Substance Use and the Pre-exposure Prophylaxis Care Continuum Among Sexual Minority Men.

Michael Viamonte, Delaram Ghanooni, John M Reynolds, Christian Grov, Adam W Carrico
Author Information
  1. Michael Viamonte: Department of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th St., Office 1010, Miami, FL, 33136, USA.
  2. Delaram Ghanooni: Department of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th St., Office 1010, Miami, FL, 33136, USA.
  3. John M Reynolds: Calder Memorial Library, University of Miami, FL, Miami, USA.
  4. Christian Grov: City University of New York Graduate School of Public Health and Health Policy, New York, NY, USA.
  5. Adam W Carrico: Department of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th St., Office 1010, Miami, FL, 33136, USA. a.carrico@miami.edu.
PMID: 35701713 DOI: 10.1007/s11904-022-00608-y

Abstract

PURPOSE OF REVIEW: Patterns of sexualized drug use, including stimulants (e.g., methamphetamine) and chemsex drugs, are key drivers of HIV incidence among sexual minority men (SMM). Although pre-exposure prophylaxis (PrEP) mitigates HIV risk, there is no consensus regarding the associations of substance use with the PrEP care continuum.
RECENT FINDINGS: SMM who use substances are as likely or more likely to use PrEP. Although SMM who use stimulants experience greater difficulties with daily oral PrEP adherence, some evidence shows that SMM who use stimulants or chemsex drugs may achieve better adherence in the context of recent condomless anal sex. Finally, SMM who use substances may experience greater difficulties with PrEP persistence (including retention in PrEP care). SMM who use stimulants and other substances would benefit from more comprehensive efforts to support PrEP re-uptake, adherence, and persistence, including delivering behavioral interventions, considering event-based dosing, and providing injectable PrEP.

Keywords

Adherence Chemsex Cocaine Methamphetamine Persistence Pre-exposure prophylaxis

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Grants

  1. UG3 AI169652/NIAID NIH HHS
  2. R34 DA046367/NIDA NIH HHS
  3. R01 DA051848/NIDA NIH HHS
  4. P30 AI073961/NIAID NIH HHS

MeSH Term

Anti-HIV Agents
Continuity of Patient Care
HIV Infections
Homosexuality, Male
Humans
Male
Pre-Exposure Prophylaxis
Running
Sexual Behavior
Sexual and Gender Minorities
Substance-Related Disorders

Chemicals

Anti-HIV Agents
Journal Article Review Systematic Review Research Support, N.I.H., Extramural
Article has an altmetric score of 1

Word Cloud

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