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Nature communications
06 23, 2022;13 (1): 3581.

Breaking the nanoparticle's dispersible limit via rotatable surface ligands.

Yue Liu, Na Peng, Yifeng Yao, Xuan Zhang, Xianqi Peng, Liyan Zhao, Jing Wang, Liang Peng, Zuankai Wang, Kenji Mochizuki, Min Yue, Shikuan Yang
Author Information
  1. Yue Liu: Institute for Composites Science Innovation, School of Materials Science and Engineering, Zhejiang University, Hangzhou, 310027, China.
  2. Na Peng: Institute of Veterinary Sciences & Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.
  3. Yifeng Yao: Department of Chemistry, Zhejiang University, Hangzhou, 310028, China.
  4. Xuan Zhang: Department of Chemistry, Zhejiang University, Hangzhou, 310028, China. ORCID
  5. Xianqi Peng: Institute of Veterinary Sciences & Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.
  6. Liyan Zhao: Institute for Composites Science Innovation, School of Materials Science and Engineering, Zhejiang University, Hangzhou, 310027, China.
  7. Jing Wang: Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA. ORCID
  8. Liang Peng: Deparment of Mechanical Engineering, City University of Hongkong, Hongkong, 999077, China.
  9. Zuankai Wang: Deparment of Mechanical Engineering, City University of Hongkong, Hongkong, 999077, China. ORCID
  10. Kenji Mochizuki: Department of Chemistry, Zhejiang University, Hangzhou, 310028, China. kenji_mochizuki@zju.edu.cn. ORCID
  11. Min Yue: Institute of Veterinary Sciences & Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China. myue@zju.edu.cn. ORCID
  12. Shikuan Yang: Institute for Composites Science Innovation, School of Materials Science and Engineering, Zhejiang University, Hangzhou, 310027, China. shkyang@zju.edu.cn. ORCID
PMID: 35739115 DOI: 10.1038/s41467-022-31275-7

Abstract

Achieving versatile dispersion of nanoparticles in a broad range of solvents (e.g., water, oil, and biofluids) without repeatedly recourse to chemical modifications are desirable in optoelectronic devices, self-assembly, sensing, and biomedical fields. However, such a target is limited by the strategies used to decorate nanoparticle's surface properties, leading to a narrow range of solvents for existing nanoparticles. Here we report a concept to break the nanoparticle's dispersible limit via electrochemically anchoring surface ligands capable of sensing the surrounding liquid medium and rotating to adapt to it, immediately forming stable dispersions in a wide range of solvents (polar and nonpolar, biofluids, etc.). Moreover, the smart nanoparticles can be continuously electrodeposited in the electrolyte, overcoming the electrode surface-confined low throughput limitation of conventional electrodeposition methods. The anomalous dispersive property of the smart Ag nanoparticles enables them to resist bacteria secreted species-induced aggregation and the structural similarity of the surface ligands to that of the bacterial membrane assists them to enter the bacteria, leading to high antibacterial activity. The simple but massive fabrication process and the enhanced dispersion properties offer great application opportunities to the smart nanoparticles in diverse fields.

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MeSH Term

Electrolytes
Ligands
Metal Nanoparticles
Nanoparticles
Silver
Solvents

Chemicals

Electrolytes
Ligands
Solvents
Silver
Journal Article Research Support, Non-U.S. Gov't
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Word Cloud

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