Metastatic primary gastric melanoma: a rare clinical presentation and a review of literature.

Bikash Ranjan Mahapatra, Anupam Muraleedharan, Saroj Kumar Das Majumdar, Amit Kumar Adhya
Author Information
  1. Bikash Ranjan Mahapatra: Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India. ORCID
  2. Anupam Muraleedharan: Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India. ORCID
  3. Saroj Kumar Das Majumdar: Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India sarojmajumdar@gmail.com.
  4. Amit Kumar Adhya: Department of Pathology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Abstract

Primary gastric melanoma is a rare clinical finding. It presents with upper gastrointestinal symptoms like abdominal pain, weight loss and melaena. It is often difficult to differentiate a primary gastric melanoma from primary cutaneous melanoma with gastric metastasis. Upper gastrointestinal endoscopy and biopsy of the lesion for histopathology and immunohistochemistry help to reach a definite diagnosis. We report a case of primary gastric melanoma with metastases to the liver and bone. The patient was treated with palliative radiotherapy, palliative chemotherapy and a bone-stabilising agent.

Keywords

References

  1. J Oral Maxillofac Surg. 2002 May;60(5):588-91 [PMID: 11988943]
  2. Am J Gastroenterol. 1999 Dec;94(12):3427-33 [PMID: 10606298]
  3. World J Gastroenterol. 2006 Jul 21;12(27):4425-7 [PMID: 16865791]
  4. Endoscopy. 1998 Sep;30(7):662-5 [PMID: 9826150]
  5. Endoscopy. 1995 Jun;27(5):409 [PMID: 7588363]
  6. BMC Cancer. 2019 Nov 12;19(1):1091 [PMID: 31718602]
  7. J Gastrointest Cancer. 2014 Dec;45 Suppl 1:33-5 [PMID: 23912608]
  8. Rare Tumors. 2015 Mar 27;7(1):5683 [PMID: 25918612]
  9. Int J Clin Exp Pathol. 2012;5(8):739-53 [PMID: 23071856]
  10. J Gastrointestin Liver Dis. 2019 Jun 01;28:237-240 [PMID: 31204403]
  11. Int J Clin Exp Pathol. 2014 Sep 15;7(10):6826-31 [PMID: 25400765]
  12. ANZ J Surg. 2021 Mar;91(3):269-275 [PMID: 32687691]
  13. Cancer. 1998 Oct 15;83(8):1664-78 [PMID: 9781962]
  14. J Gastrointest Surg. 2008 Apr;12(4):731-8 [PMID: 18058185]
  15. Melanoma Manag. 2020 Nov 23;7(4):MMT51 [PMID: 33318781]
  16. Clin Gastroenterol Hepatol. 2019 Aug;17(9):e104 [PMID: 31351572]

MeSH Term

Biopsy
Humans
Melanoma
Neoplasms, Second Primary
Skin Neoplasms
Stomach Neoplasms

Word Cloud

Created with Highcharts 10.0.0gastricmelanomaprimaryrareclinicalgastrointestinalpalliativePrimaryfindingpresentsuppersymptomslikeabdominalpainweightlossmelaenaoftendifficultdifferentiatecutaneousmetastasisUpperendoscopybiopsylesionhistopathologyimmunohistochemistryhelpreachdefinitediagnosisreportcasemetastasesliverbonepatienttreatedradiotherapychemotherapybone-stabilisingagentMetastaticmelanoma:presentationreviewliteratureCancerinterventionGastriccancerMalignantdiseaseimmunosuppressionPathologyRadiotherapy

Similar Articles

Cited By