Photobiomodulation therapy and 3% potassium nitrate gel as treatment of cervical dentin hypersensitivity: a randomized clinical trial.

Andrea Barros Tolentino, Livia Favaro Zeola, Marcella Rodrigues Ueda Fernandes, Claudio Mendes Pannuti, Paulo Vinícius Soares, Ana Cecilia Correa Aranha
Author Information
  1. Andrea Barros Tolentino: Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes 2227, São Paulo, 05508-000, Brazil.
  2. Livia Favaro Zeola: Department of Dentistry and Dental Materials, School of Dentistry, Federal University of Minas Gerais, Rua Prof. Moacir Gomes de Freitas, 688, Belo Horizonte, Minas Gerais, Brazil.
  3. Marcella Rodrigues Ueda Fernandes: Special Laboratory of Lasers in Dentistry (LELO), Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes 2227, São Paulo, 05508-000, Brazil.
  4. Claudio Mendes Pannuti: Department of Periodontics, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, São Paulo, SP, 222705508-000, Brazil.
  5. Paulo Vinícius Soares: School of Dentistry, Department of Dental Materials, Federal University of Uberlândia, Av. Pará - 1720, Uberlândia, Minas Gerais, Brazil.
  6. Ana Cecilia Correa Aranha: Special Laboratory of Lasers in Dentistry (LELO), Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes 2227, São Paulo, SP, 05508-000, Brazil. acca@usp.br. ORCID

Abstract

OBJECTIVES: This randomized controlled trial aimed to evaluate different protocols for dentin hypersensitivity treatment with low-power lasers and desensitizing agents, and the association between low-power lasers and desensitizing agents.
MATERIALS AND METHODS: Fifty-four patients (303 teeth) were randomly allocated to three groups: G1, 3% nitrate potassium gel, UltraEZ (n = 17); G2, photobiomodulation therapy (PBM) with a low-level infrared laser (n = 17), 100 mW, spot size of 0.028 cm, and dose of 1 J per point; and G3, nitrate potassium + PBM (n = 20). Treatments were applied to the buccal cervical region at intervals of 72 h, and all protocols were performed in three sessions. The patients' response to evaporative stimuli was rated using the visual analog scale (VAS). Re-evaluations were performed immediately after each application and 1 week, 1 month, and 3 months after treatment. A two-way repeated measures test and Tukey's post hoc test were used for multiple comparisons (α = 5%).
RESULTS: There was a reduction in pain levels at the end of treatment in all groups. There were no significant differences in VAS score changes between the groups immediately after treatment and after the third month, compared to the baseline (p > 0.05).
CONCLUSION: Under the limitations of this in vivo study, the proposed three-session protocol was effective in reducing dentin hypersensitivity after 3 months, regardless of the desensitization mechanism used. Conservative and long-term protocols are interesting for the control of pain caused by dentin hypersensitivity.
CLINICAL RELEVANCE: The increase in cervical dentin hypersensitivity prevalence warrants easy-to-apply and long-lasting desensitizing protocols for pain control.

Keywords

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MeSH Term

Humans
Dentin Sensitivity
Low-Level Light Therapy
Nitrates
Pain
Potassium
Dentin Desensitizing Agents
Treatment Outcome

Chemicals

potassium nitrate
Nitrates
Potassium
Dentin Desensitizing Agents

Word Cloud

Created with Highcharts 10.0.0dentinhypersensitivitytreatmentprotocolsnitratetrialdesensitizingcervicalpainrandomizedlow-powerlasersagentsthree3%potassiumgeln = 17therapylaserperformedVASimmediately3 monthstestusedgroupscontrolOBJECTIVES:controlledaimedevaluatedifferentassociationMATERIALSANDMETHODS:Fifty-fourpatients303teethrandomlyallocatedgroups:G1UltraEZG2photobiomodulationPBMlow-levelinfrared100mWspotsize0028cmdose1 JperpointG3potassium + PBMn = 20Treatmentsappliedbuccalregionintervals72 hsessionspatients'responseevaporativestimuliratedusingvisualanalogscaleRe-evaluationsapplication1 week1 monthtwo-wayrepeatedmeasuresTukey'sposthocmultiplecomparisonsα = 5%RESULTS:reductionlevelsendsignificantdifferencesscorechangesthirdmonthcomparedbaselinep > 005CONCLUSION:limitationsvivostudyproposedthree-sessionprotocoleffectivereducingregardlessdesensitizationmechanismConservativelong-terminterestingcausedCLINICALRELEVANCE:increaseprevalencewarrantseasy-to-applylong-lastingPhotobiomodulationhypersensitivity:clinicalCervicalClinicalLow-powerPotassium

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