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Sep 16, 2022;25 (9): 105007.

Geographical distribution and phylogenetic analysis of Jingmen tick virus in China.

Zheng Pang, Yuting Jin, Mei Pan, Yuli Zhang, Zhen Wu, Lin Liu, Guoyu Niu
Author Information
  1. Zheng Pang: School of Public Health, Weifang Medical University, Weifang 261053, China.
  2. Yuting Jin: Suzhou Institute of Systems Medicine, Suzhou 215123, China.
  3. Mei Pan: Suzhou Institute of Systems Medicine, Suzhou 215123, China.
  4. Yuli Zhang: School of Public Health, Weifang Medical University, Weifang 261053, China.
  5. Zhen Wu: School of Public Health, Weifang Medical University, Weifang 261053, China.
  6. Lin Liu: Immune-Path Biotechnology (Suzhou) Co., Ltd, Suzhou 215000, China.
  7. Guoyu Niu: School of Public Health, Weifang Medical University, Weifang 261053, China.
PMID: 36097615 DOI: 10.1016/j.isci.2022.105007

Abstract

Jingmen tick virus (JMTV) is a novel tick-borne segmented RNA virus that is closely related to un-segmental RNA virus in evolution. It has been confirmed that JMTV could be a causative agent of human disease. In this study, a total of 3658 ticks were sampled from 7 provinces of China and then divided into 545 pools according to the location and species. QRT-PCR and nested PCR were performed to confirm the presence of JMTV. The results showed JMTV was identified in 5 out of 7 provinces with an average infection rate of 1.4% (51/3658). Phylogenetic analysis indicated that all JMTV strains identified in this study were closely related to each other and formed a well-supported sub-lineage. Our results provide molecular evidence of JMTV in different species of ticks from endemic and non-endemic regions and demonstrate that JMTV, as a natural foci pathogen, may be widely distributed all over China.

Keywords

Tick evolutionary biology virology

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Journal Article
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