Current Approaches to the Management of Patients with Endometrial Cancer.
Emmanouil Kalampokas, Georgios Giannis, Theodoros Kalampokas, Angeliki-Astero Papathanasiou, Dimitra Mitsopoulou, Evangelia Tsironi, Olga Triantafyllidou, Mahalakshmi Gurumurthy, David E Parkin, Mary Cairns, Nikolaos F Vlahos
Author Information
Emmanouil Kalampokas: Unit of Gynecologic Oncology, Second Department of Obstetrics and Gynecology, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece. ORCID
Georgios Giannis: Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece. ORCID
Theodoros Kalampokas: Unit of Obstetrics and Gynecology, Second Department of Obstetrics and Gynecology, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece. ORCID
Angeliki-Astero Papathanasiou: Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece. ORCID
Dimitra Mitsopoulou: Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece. ORCID
Evangelia Tsironi: Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece.
Olga Triantafyllidou: Unit of Obstetrics and Gynecology, Second Department of Obstetrics and Gynecology, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece.
Mahalakshmi Gurumurthy: Department of Gynaecological Oncology, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK.
David E Parkin: Honorary Consultant Gynaecologist Oncologist, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK.
Mary Cairns: Department of Gynaecological Oncology, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK.
Nikolaos F Vlahos: Unit of Obstetrics and Gynecology, Second Department of Obstetrics and Gynecology, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece. ORCID
The incidence of endometrial cancer (EC) is rising and healthcare professionals need to be informed about the latest data on the constant developments in the field of its management. With particular interest in the classification and management of EC, we surveyed current literature, national and international data, and guidelines, as well as the latest studies to present the most recent data regarding the management of EC. It became evident that despite the consensus on low-risk EC, there are still controversies surrounding the management of high-risk EC, especially regarding the role of sentinel lymph node biopsy (SLNB). Our aim is to present the old and new perspectives in the management of EC, the different available surgical routes, the possible desire for fertility preservation, the role of adjuvant therapies and the focus on the advantages and the limitations of the implementation of SLNB in therapeutic strategies. It became evident throughout our search and based on literature data that minimally invasive surgery (MIS) leads to satisfying outcomes, thus becoming gradually the preferred route of surgery, while SLNB could provide essential information and guidance about the overall management needed in cases of both low-risk and high-risk EC.
