Vaccines against Emerging and Neglected Infectious Diseases: An Overview.
Larissa Vuitika, Wasim A Prates-Syed, Jaqueline Dinis Queiros Silva, Karin P Crema, Nelson Côrtes, Aline Lira, Julia Beatriz Menuci Lima, Niels Olsen Saraiva Camara, Lena F Schimke, Otavio Cabral-Marques, Mohammad Sadraeian, Lorena C S Chaves, Gustavo Cabral-Miranda
Author Information
Larissa Vuitika: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil.
Wasim A Prates-Syed: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil. ORCID
Jaqueline Dinis Queiros Silva: Laboratory of Research in Infectious Diseases (LAPI), Hospital Prof. Edgard Santos, Federal University of Bahia, Salvador 40110-060, BA, Brazil.
Karin P Crema: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil.
Nelson Côrtes: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil. ORCID
Aline Lira: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil. ORCID
Julia Beatriz Menuci Lima: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil. ORCID
Niels Olsen Saraiva Camara: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil. ORCID
Lena F Schimke: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil. ORCID
Otavio Cabral-Marques: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil. ORCID
Mohammad Sadraeian: Institute for Biomedical Materials and Devices (IBMD), Faculty of Science, University of Technology, Sydney, NSW 2007, Australia. ORCID
Lorena C S Chaves: Department of Microbiology and Immunology, School of Medicine, Emory University, Claudia Nance Rollins Building, Atlanta, GA 30329, USA. ORCID
Gustavo Cabral-Miranda: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil.
Neglected Tropical Diseases (NTDs) are a group of diseases that are highly prevalent in tropical and subtropical regions, and closely associated with poverty and marginalized populations. Infectious diseases affect over 1.6 billion people annually, and vaccines are the best prophylactic tool against them. Along with NTDs, emerging and reemerging Infectious diseases also threaten global public health, as they can unpredictably result in pandemics. The recent advances in vaccinology allowed the development and licensing of new vaccine platforms that can target and prevent these diseases. In this work, we discuss the advances in vaccinology and some of the difficulties found in the vaccine development pipeline for selected NTDs and emerging and reemerging Infectious diseases, including HIV, Dengue, Ebola, Chagas disease, malaria, leishmaniasis, zika, and chikungunya.
